Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2010165..2010310 Replicon chromosome
Accession NZ_CP064241
Organism Klebsiella pneumoniae strain JX-CR-hvKP-3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2010201..2010303 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2010165..2010310 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IS502_RS09840 2005295..2007355 + 2061 WP_004151449.1 oligopeptidase B -
IS502_RS09845 2007359..2008018 - 660 WP_002911407.1 exodeoxyribonuclease X -
IS502_RS09850 2008097..2008327 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IS502_RS09855 2008440..2008814 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IS502_RS09860 2008818..2009687 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
IS502_RS09865 2009704..2010042 + 339 WP_002911404.1 YebY family protein -
- 2010165..2010310 - 146 - - Antitoxin
- 2010201..2010303 + 103 - - Toxin
IS502_RS09870 2010678..2010821 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IS502_RS09875 2010926..2011894 - 969 WP_004151446.1 VirK/YbjX family protein -
IS502_RS09880 2012051..2012704 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
IS502_RS09885 2012701..2012892 - 192 WP_002911395.1 YebW family protein -
IS502_RS09890 2012990..2013229 - 240 WP_002911393.1 YebV family protein -
IS502_RS09895 2013345..2014778 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T180671 NZ_CP064241:2010201-2010303 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT180671 NZ_CP064241:c2010310-2010165 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References