Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2007497..2007642 Replicon chromosome
Accession NZ_CP064223
Organism Klebsiella pneumoniae strain JX-CR-hvKP-7

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2007533..2007635 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2007497..2007642 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IS505_RS09820 2002627..2004687 + 2061 WP_004151449.1 oligopeptidase B -
IS505_RS09825 2004691..2005350 - 660 WP_002911407.1 exodeoxyribonuclease X -
IS505_RS09830 2005429..2005659 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IS505_RS09835 2005772..2006146 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IS505_RS09840 2006150..2007019 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
IS505_RS09845 2007036..2007374 + 339 WP_002911404.1 YebY family protein -
- 2007497..2007642 - 146 - - Antitoxin
- 2007533..2007635 + 103 - - Toxin
IS505_RS09850 2008010..2008153 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IS505_RS09855 2008258..2009226 - 969 WP_004151446.1 VirK/YbjX family protein -
IS505_RS09860 2009383..2010036 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
IS505_RS09865 2010033..2010224 - 192 WP_002911395.1 YebW family protein -
IS505_RS09870 2010322..2010561 - 240 WP_002911393.1 YebV family protein -
IS505_RS09875 2010677..2012110 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T180564 NZ_CP064223:2007533-2007635 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT180564 NZ_CP064223:c2007642-2007497 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References