Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2084130..2084275 Replicon chromosome
Accession NZ_CP064205
Organism Klebsiella pneumoniae strain JX-CR-hvKP-12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2084166..2084268 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2084130..2084275 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IS504_RS10020 2079260..2081320 + 2061 WP_004151449.1 oligopeptidase B -
IS504_RS10025 2081324..2081983 - 660 WP_002911407.1 exodeoxyribonuclease X -
IS504_RS10030 2082062..2082292 - 231 WP_002911406.1 DNA polymerase III subunit theta -
IS504_RS10035 2082405..2082779 + 375 WP_004151448.1 CopC domain-containing protein YobA -
IS504_RS10040 2082783..2083652 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
IS504_RS10045 2083669..2084007 + 339 WP_002911404.1 YebY family protein -
- 2084130..2084275 - 146 - - Antitoxin
- 2084166..2084268 + 103 - - Toxin
IS504_RS10050 2084643..2084786 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
IS504_RS10055 2084891..2085859 - 969 WP_014907334.1 VirK/YbjX family protein -
IS504_RS10060 2086016..2086669 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
IS504_RS10065 2086666..2086857 - 192 WP_002911395.1 YebW family protein -
IS504_RS10070 2086955..2087194 - 240 WP_002911393.1 YebV family protein -
IS504_RS10075 2087310..2088743 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T180459 NZ_CP064205:2084166-2084268 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT180459 NZ_CP064205:c2084275-2084130 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References