Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2499452..2499546 Replicon chromosome
Accession NZ_CP064123
Organism Yersinia pestis strain M2029

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2499453..2499546 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2499452..2499546 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISU60_RS11210 2494645..2496723 - 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -
ISU60_RS11215 2496723..2497883 - 1161 WP_002211099.1 flagellar type III secretion system protein FlhB -
ISU60_RS11220 2498415..2498873 + 459 WP_002211098.1 hypothetical protein -
ISU60_RS11225 2498867..2499193 + 327 WP_002211097.1 DUF1493 family protein -
- 2499452..2499546 + 95 - - Antitoxin
- 2499453..2499546 - 94 - - Toxin
ISU60_RS11230 2499716..2500057 - 342 WP_002211095.1 YebY family protein -
ISU60_RS11235 2500154..2501038 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
ISU60_RS11240 2501041..2501427 - 387 WP_002211093.1 CopC domain-containing protein YobA -
ISU60_RS11245 2501833..2502342 - 510 WP_002211092.1 non-heme ferritin -
ISU60_RS11250 2502743..2502973 + 231 WP_002211091.1 DNA polymerase III subunit theta -
ISU60_RS11255 2503033..2503983 - 951 WP_002211090.1 prolyl aminopeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences

Toxin        


Download         Length: 94 bp

>T180275 NZ_CP064123:c2499546-2499453 [Yersinia pestis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT180275 NZ_CP064123:2499452-2499546 [Yersinia pestis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures

Antitoxin

Download structure file

Antitoxin

Download structure file

References