Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2226046..2226140 Replicon chromosome
Accession NZ_CP064121
Organism Yersinia pestis strain M-1482

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2226047..2226140 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2226046..2226140 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISU58_RS10200 2221239..2223317 - 2079 WP_002211100.1 flagellar biosynthesis protein FlhA -
ISU58_RS10205 2223317..2224477 - 1161 WP_002211099.1 flagellar type III secretion system protein FlhB -
ISU58_RS10210 2225009..2225467 + 459 WP_002211098.1 hypothetical protein -
ISU58_RS10215 2225461..2225787 + 327 WP_002211097.1 DUF1493 family protein -
- 2226046..2226140 + 95 - - Antitoxin
- 2226047..2226140 - 94 - - Toxin
ISU58_RS10220 2226310..2226651 - 342 WP_002211095.1 YebY family protein -
ISU58_RS10225 2226748..2227632 - 885 WP_002211094.1 copper homeostasis membrane protein CopD -
ISU58_RS10230 2227635..2228021 - 387 WP_002211093.1 CopC domain-containing protein YobA -
ISU58_RS10235 2228418..2228927 - 510 WP_002211092.1 non-heme ferritin -
ISU58_RS10240 2229328..2229558 + 231 WP_002211091.1 DNA polymerase III subunit theta -
ISU58_RS10245 2229618..2230568 - 951 WP_002211090.1 prolyl aminopeptidase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 94 bp

>T180249 NZ_CP064121:c2226140-2226047 [Yersinia pestis]
TAAGCCTACATTAATACCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATCAGGAATCGTA
TTCGGTCTTTTTTT

Antitoxin


Download         Length: 95 bp

>AT180249 NZ_CP064121:2226046-2226140 [Yersinia pestis]
TAAAAAAAGACCGAATACGATTCCTGATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGT
ATTAATGTAGGCTTA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References