Detailed information of TA system TA180049

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrE-as-bsrE/-
• Location: 3199709..3199955
• Replicon: chromosome
• Accession: NZ_CP064093
• Organism: Bacillus subtilis strain N1282-4at

Toxin (Protein)

• Gene name: bsrE
• Uniprot ID: -
• Locus tag: IRJ24_RS17225
• Protein ID: WP_109789044.1
• Coordinates: 3199863..3199955 (-)
• Length: 31 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	3199709..3199882 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IRJ24_RS17205	3195623..3196180	+	558	WP_004399321.1	SMI1/KNR4 family protein	-
IRJ24_RS17210	3196282..3198084	+	1803	WP_004399481.1	LXG family T7SS effector ribonuclease toxin YobL	-
IRJ24_RS17215	3198094..3198552	+	459	WP_003231326.1	type VII secretion system immunity protein YobK	-
IRJ24_RS17220	3198752..3199594	+	843	WP_003231327.1	hypothetical protein	-
-	3199709..3199882	+	174	-	-	Antitoxin
IRJ24_RS17225	3199863..3199955	-	93	WP_109789044.1	type I toxin-antitoxin system toxin BsrE	Toxin
IRJ24_RS17230	3200244..3200576	+	333	WP_026009814.1	hypothetical protein	-
IRJ24_RS17235	3200809..3204414	+	3606	WP_004399367.1	P-loop NTPase fold protein	-
IRJ24_RS17240	3204461..3204796	-	336	WP_009967409.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3191212..3266437	75225

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-24)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3358.16 Da
• Isoelectric Point: 4.1840

>T180049 WP_109789044.1 NZ_CP064093:c3199955-3199863 [Bacillus subtilis]
MSTFQALMLMLAIGSFIIALLTYIEKIDLP

Nucleotide

• Length: 93 bp

>T180049 NZ_CP085056:c4403048-4402875 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin

Nucleotide

• Length: 174 bp

>AT180049 NZ_CP064093:3199709-3199882 [Bacillus subtilis]
TTACAATACATTACAGTGCATTTCTTTAATGAGAAATGCATAAAATAAAAAAGACCGAGGTGCTACCAACACCCCGGCTC
TGTACAAAAAGTTGCCCATCAAAGGGCTTGCTCGATGTGGTTCTAGGTAGGCCTATCCCTTCAGGTTCTGAGGCTCAAGG
GAGGTCTATTTTTT

Structures

Antitoxin