Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4143740..4143884 Replicon chromosome
Accession NZ_CP063921
Organism Klebsiella variicola strain BM366-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4143776..4143878 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4143740..4143884 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA73_RS19745 4138870..4140930 + 2061 WP_032746815.1 oligopeptidase B -
ISA73_RS19750 4140934..4141593 - 660 WP_008804267.1 exodeoxyribonuclease X -
ISA73_RS19755 4141672..4141902 - 231 WP_012541260.1 DNA polymerase III subunit theta -
ISA73_RS19760 4142016..4142390 + 375 WP_016161388.1 CopC domain-containing protein YobA -
ISA73_RS19765 4142394..4143263 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
ISA73_RS19770 4143280..4143618 + 339 WP_008804271.1 YebY family protein -
- 4143740..4143884 - 145 - - Antitoxin
- 4143776..4143878 + 103 - - Toxin
ISA73_RS19775 4144263..4144406 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
ISA73_RS19780 4144510..4145478 - 969 WP_194387062.1 VirK/YbjX family protein -
ISA73_RS19785 4145635..4146288 + 654 WP_012967753.1 protein-serine/threonine phosphatase -
ISA73_RS19790 4146285..4146476 - 192 WP_002911395.1 YebW family protein -
ISA73_RS19795 4146574..4146813 - 240 WP_002911393.1 YebV family protein -
ISA73_RS19800 4146929..4148362 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179531 NZ_CP063921:4143776-4143878 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT179531 NZ_CP063921:c4143884-4143740 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References