Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4969332..4969476 Replicon chromosome
Accession NZ_CP063912
Organism Klebsiella variicola strain BS359-2-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4969368..4969470 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4969332..4969476 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA79_RS23930 4964462..4966522 + 2061 WP_012541258.1 oligopeptidase B -
ISA79_RS23935 4966526..4967185 - 660 WP_012541259.1 exodeoxyribonuclease X -
ISA79_RS23940 4967264..4967494 - 231 WP_012541260.1 DNA polymerase III subunit theta -
ISA79_RS23945 4967608..4967982 + 375 WP_012541261.1 CopC domain-containing protein YobA -
ISA79_RS23950 4967986..4968855 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
ISA79_RS23955 4968872..4969210 + 339 WP_008804271.1 YebY family protein -
- 4969332..4969476 - 145 - - Antitoxin
- 4969368..4969470 + 103 - - Toxin
ISA79_RS23960 4969855..4969998 - 144 WP_046621074.1 Ecr family regulatory small membrane protein -
ISA79_RS23965 4970102..4971070 - 969 WP_162493241.1 VirK/YbjX family protein -
ISA79_RS23970 4971227..4971880 + 654 WP_012967753.1 protein-serine/threonine phosphatase -
ISA79_RS23975 4971877..4972068 - 192 WP_002911395.1 YebW family protein -
ISA79_RS23980 4972166..4972405 - 240 WP_002911393.1 YebV family protein -
ISA79_RS23985 4972521..4973954 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179421 NZ_CP063912:4969368-4969470 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT179421 NZ_CP063912:c4969476-4969332 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References