Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1420034..1420178 Replicon chromosome
Accession NZ_CP063910
Organism Klebsiella variicola strain BS325-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1420040..1420142 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1420034..1420178 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISA81_RS07045 1415556..1416989 + 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
ISA81_RS07050 1417105..1417344 + 240 WP_002911393.1 YebV family protein -
ISA81_RS07055 1417442..1417633 + 192 WP_002911395.1 YebW family protein -
ISA81_RS07060 1417630..1418283 - 654 WP_012967753.1 protein-serine/threonine phosphatase -
ISA81_RS07065 1418440..1419408 + 969 WP_194387062.1 VirK/YbjX family protein -
ISA81_RS07070 1419512..1419655 + 144 WP_048268691.1 Ecr family regulatory small membrane protein -
- 1420034..1420178 + 145 - - Antitoxin
- 1420040..1420142 - 103 - - Toxin
ISA81_RS07075 1420300..1420638 - 339 WP_008804271.1 YebY family protein -
ISA81_RS07080 1420655..1421524 - 870 WP_012541262.1 copper homeostasis membrane protein CopD -
ISA81_RS07085 1421528..1421902 - 375 WP_016161388.1 CopC domain-containing protein YobA -
ISA81_RS07090 1422016..1422246 + 231 WP_012541260.1 DNA polymerase III subunit theta -
ISA81_RS07095 1422325..1422984 + 660 WP_008804267.1 exodeoxyribonuclease X -
ISA81_RS07100 1422988..1425048 - 2061 WP_032746815.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179379 NZ_CP063910:c1420142-1420040 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT179379 NZ_CP063910:1420034-1420178 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References