Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 3437618..3437763 | Replicon | chromosome |
| Accession | NZ_CP063878 | ||
| Organism | Klebsiella pneumoniae strain M169-3 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 3437654..3437756 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 3437618..3437763 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ISB47_RS16965 | 3432748..3434808 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| ISB47_RS16970 | 3434812..3435471 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| ISB47_RS16975 | 3435550..3435780 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| ISB47_RS16980 | 3435893..3436267 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| ISB47_RS16985 | 3436271..3437140 | + | 870 | WP_023282759.1 | copper homeostasis membrane protein CopD | - |
| ISB47_RS16990 | 3437157..3437495 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 3437618..3437763 | - | 146 | - | - | Antitoxin |
| - | 3437654..3437756 | + | 103 | - | - | Toxin |
| ISB47_RS16995 | 3438131..3438274 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| ISB47_RS17000 | 3438379..3439347 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| ISB47_RS17005 | 3439504..3440157 | + | 654 | WP_032418800.1 | protein-serine/threonine phosphatase | - |
| ISB47_RS17010 | 3440154..3440345 | - | 192 | WP_002911395.1 | YebW family protein | - |
| ISB47_RS17015 | 3440443..3440682 | - | 240 | WP_002911393.1 | YebV family protein | - |
| ISB47_RS17020 | 3440798..3442231 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T179147 NZ_CP063878:3437654-3437756 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT179147 NZ_CP063878:c3437763-3437618 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
