Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 912407..912552 Replicon chromosome
Accession NZ_CP063858
Organism Klebsiella pneumoniae strain M1026-3Ar

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 912414..912516 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 912407..912552 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IOD46_RS04575 907938..909371 + 1434 WP_194315361.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IOD46_RS04580 909487..909726 + 240 WP_002911393.1 YebV family protein -
IOD46_RS04585 909824..910015 + 192 WP_002911395.1 YebW family protein -
IOD46_RS04590 910012..910665 - 654 WP_009484457.1 protein-serine/threonine phosphatase -
IOD46_RS04595 910822..911790 + 969 WP_004151446.1 VirK/YbjX family protein -
IOD46_RS04600 911895..912038 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 912407..912552 + 146 - - Antitoxin
- 912414..912516 - 103 - - Toxin
IOD46_RS04605 912675..913013 - 339 WP_002911404.1 YebY family protein -
IOD46_RS04610 913030..913899 - 870 WP_004189267.1 copper homeostasis membrane protein CopD -
IOD46_RS04615 913903..914277 - 375 WP_004151448.1 CopC domain-containing protein YobA -
IOD46_RS04620 914390..914620 + 231 WP_002911406.1 DNA polymerase III subunit theta -
IOD46_RS04625 914699..915358 + 660 WP_021440386.1 exodeoxyribonuclease X -
IOD46_RS04630 915362..917422 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T179006 NZ_CP063858:c912516-912414 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT179006 NZ_CP063858:912407-912552 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References