Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1255066..1255714 Replicon chromosome
Accession NZ_CP063845
Organism Gloeobacter morelensis MG652769

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag ISF26_RS06190 Protein ID WP_230843035.1
Coordinates 1255066..1255476 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag ISF26_RS06195 Protein ID WP_230843036.1
Coordinates 1255478..1255714 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ISF26_RS06180 (ISF26_06125) 1252344..1254122 + 1779 WP_230843033.1 hypothetical protein -
ISF26_RS06185 (ISF26_06130) 1254219..1254902 - 684 WP_230843034.1 hypothetical protein -
ISF26_RS06190 (ISF26_06135) 1255066..1255476 - 411 WP_230843035.1 type II toxin-antitoxin system VapC family toxin Toxin
ISF26_RS06195 (ISF26_06140) 1255478..1255714 - 237 WP_230843036.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
ISF26_RS06200 (ISF26_06145) 1256763..1257446 + 684 WP_230843037.1 hypothetical protein -
ISF26_RS06205 (ISF26_06150) 1257505..1258617 + 1113 WP_230843038.1 hypothetical protein -
ISF26_RS06210 (ISF26_06155) 1258647..1260401 + 1755 WP_230843039.1 DUF87 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-126)

Antitoxin

SpoVT-AbrB domain

(10-55)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 14635.89 Da        Isoelectric Point: 6.4585

>T178949 WP_230843035.1 NZ_CP063845:c1255476-1255066 [Gloeobacter morelensis MG652769]
MNAYRYLLDTNIVSNLIRFPGGSVAANIARIGEAGVCTSIIVASELRFGAAKKGSMRLSAQLETVLSGLDVLPFEFPGDQ
HYATLRAAIERTGTPIGSNDMFIAAHALYLGLILVTDNLREFARIPGLSVENWLAP

Download         Length: 411 bp

>T178949 NZ_CP084433:1710070-1710158 [Edwardsiella piscicida]
GCAAGGCACTCAATGCCTGCATAATGCCAACTTTTAGCGCACGGCTCTCCAAAAGAGCCATTCCCCTAGACCTGACACAG
GAATCGTGT

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9188.52 Da        Isoelectric Point: 4.5482

>AT178949 WP_230843036.1 NZ_CP063845:c1255714-1255478 [Gloeobacter morelensis MG652769]
MPTERHVRLFRNGRNQALRIPREFELPSEEAIIRKEGDRLIIEPLRRRSLLALLATLEPLEDEFPDIDDLPPLDDVNF

Download         Length: 237 bp

>AT178949 NZ_CP084433:c1710158-1710063 [Edwardsiella piscicida]
ACACGATTCCTGTGTCAGGTCTAGGGGAATGGCTCTTTTGGAGAGCCGTGCGCTAAAAGTTGGCATTATGCAGGCATTGA
GTGCCTTGCTCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References