Detailed information of TA system TA178775

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 1760614..1761145
• Replicon: chromosome
• Accession: NZ_CP063773
• Organism: Pectobacterium carotovorum subsp. carotovorum PCCS1

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: IQ281_RS07990
• Protein ID: WP_194431462.1
• Coordinates: 1760858..1761145 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: -
• Locus tag: IQ281_RS07985
• Protein ID: WP_180778477.1
• Coordinates: 1760614..1760868 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IQ281_RS07960	1755753..1756343	-	591	WP_012773024.1	DnaA initiator-associating protein DiaA	-
IQ281_RS07965	1756407..1756802	-	396	WP_194431748.1	YraN family protein	-
IQ281_RS07970	1756760..1758778	-	2019	WP_194431460.1	penicillin-binding protein activator	-
IQ281_RS07975	1758840..1759727	+	888	WP_194431461.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
IQ281_RS07985	1760614..1760868	+	255	WP_180778477.1	plasmid stabilization protein	Antitoxin
IQ281_RS07990	1760858..1761145	+	288	WP_194431462.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
IQ281_RS07995	1761324..1762109	+	786	WP_194431463.1	4,5-DOPA dioxygenase extradiol	-
IQ281_RS08000	1762179..1763339	-	1161	WP_180778474.1	glutathionylspermidine synthase family protein	-
IQ281_RS08005	1763351..1764025	-	675	WP_012773030.1	DUF1190 family protein	-
IQ281_RS08010	1764292..1765683	-	1392	WP_182100458.1	outer membrane channel protein TolC	-
IQ281_RS08015	1765818..1765973	-	156	WP_012773032.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-87)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11011.96 Da
• Isoelectric Point: 10.7694

>T178775 WP_194431462.1 NZ_CP063773:1760858-1761145 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLKSAGYRLVYLVQDETITVMIMGVGK
REGSQVYSDTKGRSA

Nucleotide

• Length: 288 bp

>T178775 NZ_CP084287:400199-400498 [Caballeronia zhejiangensis]
ATGAAGGAGTTTGTCCTCTCGCCTGCGGCGGAGTTGGATCTAGACGACGTATGGGATTACTCGGCTGAGCACTGGGGCCT
CAATCAGGCCGAGCGCTACATTCGAATGATCCAAGACACAATCGTTGGATTGGCGCACGGCACACAGCTAAGCCAGGGTG
CTTCTCACATCCGAGCAGGCTACCGCCGTGCGCTGGTTGGTTCGCACGTTCTGTTCTTCAAGGAAACCGATACGTTGATT
GATGTAATCCGCATCCTCCATCAGCGGATGGATCCGTCACAGCATCTGTGTGATCACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9240.44 Da
• Isoelectric Point: 3.7947

>AT178775 WP_180778477.1 NZ_CP063773:1760614-1760868 [Pectobacterium carotovorum subsp. carotovorum PCCS1]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAMFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT178775 NZ_CP084287:399960-400202 [Caballeronia zhejiangensis]
ATGGCCAAAAACACGTCCGTTTCACTTGGCGAGCACTTCGCGGATTTCGTTGAAGACCGTGTGCGCGTAGGACGCTACAA
CACGGCAAGCGACGTGGTCCGGGCTGGCCTTCGGTTGTTGGAAGAGCAAGAGGCGAAGCTCGACACTTTGCGCGCGGAAC
TAGAGAAAGGCGAGCGCTCAGGCCCGTCGCGGCCCTTCAACTTCGACGCTTTCCTTGCACGTAAGCGAAAGTCGACGAAA
TGA