Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 2100239..2100635 Replicon chromosome
Accession NZ_CP063659
Organism Synechocystis sp. PCC 7339

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IQE94_RS09960 Protein ID WP_255611404.1
Coordinates 2100239..2100370 (-) Length 44 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IQE94_RS09965 Protein ID WP_223341833.1
Coordinates 2100417..2100635 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IQE94_RS09930 (IQE94_09825) 2096233..2096601 - 369 WP_190595906.1 photosystem II reaction center protein Psb28 -
IQE94_RS09935 (IQE94_09830) 2096848..2097324 + 477 WP_223341832.1 DUF1499 domain-containing protein -
IQE94_RS09940 (IQE94_09835) 2097340..2097759 - 420 WP_194014014.1 Fur family transcriptional regulator -
IQE94_RS09945 (IQE94_09840) 2098072..2098641 + 570 WP_212717905.1 peroxiredoxin -
IQE94_RS09950 (IQE94_09845) 2098876..2099425 - 550 Protein_1970 transposase -
IQE94_RS09955 (IQE94_09850) 2099415..2099903 - 489 WP_212717907.1 IS630 transposase-related protein -
IQE94_RS18630 (IQE94_09855) 2099881..2100114 - 234 WP_255611276.1 transposase -
IQE94_RS09960 (IQE94_09860) 2100239..2100370 - 132 WP_255611404.1 putative toxin-antitoxin system toxin component, PIN family Toxin
IQE94_RS09965 (IQE94_09865) 2100417..2100635 - 219 WP_223341833.1 hypothetical protein Antitoxin
IQE94_RS09970 (IQE94_09870) 2100915..2102192 + 1278 WP_212717913.1 adenosylhomocysteinase -
IQE94_RS09975 (IQE94_09875) 2102389..2104670 - 2282 Protein_1976 RelA/SpoT family protein -
IQE94_RS09980 (IQE94_09880) 2105045..2105428 + 384 WP_212717917.1 heterocyst frequency control protein PatD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2099881..2110502 10621


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN family, putative toxin-antitoxin system toxin component

(1-43)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 44 a.a.        Molecular weight: 5024.90 Da        Isoelectric Point: 8.6853

>T178681 WP_255611404.1 NZ_CP063659:c2100370-2100239 [Synechocystis sp. PCC 7339]
IGKTLQGLNQTIIDNRVAILFSEDLFAELMEVLHRPKFKKYFS

Download         Length: 132 bp

>T178681 NZ_CP084209:183644-183751 [Escherichia coli]
ATGACGTTCGCAGAGCTGGGCATGGCCTTCTGGCATGATTTAGCGGCTCCGGTCATTGCTGGCATTCTTGCCAGTATGAT
CGTGAACTGGCTGAACAAGCGGAAGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8486.79 Da        Isoelectric Point: 5.8500

>AT178681 WP_223341833.1 NZ_CP063659:c2100635-2100417 [Synechocystis sp. PCC 7339]
MKSLSSLDFLELKNIIAQCNLEEKLELLELLKKDTFATRFNKFLNSVKTDELTLEDITREVEAVRQANYHKR

Download         Length: 219 bp

>AT178681 NZ_CP084209:c183595-183529 [Escherichia coli]
GTCTAGAGTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References