Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2588167..2588438 Replicon chromosome
Accession NZ_CP063473
Organism Escherichia coli strain EM18-18-42

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2588205..2588308 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2588167..2588438 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IQS24_RS12620 2585324..2586763 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IQS24_RS12625 2586881..2587117 + 237 WP_001295499.1 DUF1480 family protein -
IQS24_RS12630 2587222..2587413 + 192 WP_001296140.1 YebW family protein -
IQS24_RS12635 2587414..2588070 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2588167..2588438 + 272 - - Antitoxin
- 2588205..2588308 - 104 - - Toxin
IQS24_RS12640 2588465..2588806 - 342 WP_000976472.1 YebY family protein -
IQS24_RS12645 2588819..2589691 - 873 WP_205595400.1 copper homeostasis membrane protein CopD -
IQS24_RS12650 2589695..2590069 - 375 WP_000255065.1 CopC domain-containing protein YobA -
IQS24_RS12655 2590208..2590438 + 231 WP_000916763.1 DNA polymerase III subunit theta -
IQS24_RS12660 2590540..2591196 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
IQS24_RS12665 2591220..2591882 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T178338 NZ_CP063473:c2588308-2588205 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT178338 NZ_CP063473:2588167-2588438 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References