Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1043244..1043512 Replicon chromosome
Accession NZ_CP063214
Organism Escherichia coli strain ERP001

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1043282..1043384 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1043244..1043512 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IL987_RS05290 1040401..1041840 + 1440 WP_001298454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
IL987_RS05295 1041958..1042194 + 237 WP_001295499.1 DUF1480 family protein -
IL987_RS05300 1042299..1042490 + 192 WP_001296140.1 YebW family protein -
IL987_RS05305 1042491..1043147 - 657 WP_000812743.1 protein-serine/threonine phosphatase -
- 1043244..1043512 + 269 - - Antitoxin
- 1043282..1043384 - 103 - - Toxin
IL987_RS05310 1043542..1043883 - 342 WP_000984819.1 YebY family protein -
IL987_RS05315 1043896..1044768 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
IL987_RS05320 1044772..1045146 - 375 WP_000168747.1 CopC domain-containing protein YobA -
IL987_RS05325 1045285..1045515 + 231 WP_000916763.1 DNA polymerase III subunit theta -
IL987_RS05330 1045618..1046274 + 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
IL987_RS05335 1046298..1046960 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T177706 NZ_CP063214:c1043384-1043282 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT177706 NZ_CP063214:1043244-1043512 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References