Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 325250..325521 Replicon chromosome
Accession NZ_CP062876
Organism Escherichia coli O157:H16 strain Res13-Lact-PEA12-26

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 325380..325483 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 325250..325521 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMP69_RS01585 321805..322467 - 663 WP_000944256.1 exodeoxyribonuclease X -
IMP69_RS01590 322491..323147 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
IMP69_RS01595 323249..323479 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IMP69_RS01600 323618..323992 + 375 WP_195686609.1 CopC domain-containing protein YobA -
IMP69_RS01605 323996..324868 + 873 WP_195686610.1 copper homeostasis membrane protein CopD -
IMP69_RS01610 324881..325222 + 342 WP_000976472.1 YebY family protein -
- 325250..325521 - 272 - - Antitoxin
- 325380..325483 + 104 - - Toxin
IMP69_RS01615 325618..326274 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
IMP69_RS01620 326275..326466 - 192 WP_001313035.1 YebW family protein -
IMP69_RS01625 326571..326807 - 237 WP_001295499.1 DUF1480 family protein -
IMP69_RS01630 326925..328364 - 1440 WP_001383086.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T177073 NZ_CP062876:325380-325483 [Escherichia coli O157:H16]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT177073 NZ_CP062876:c325521-325250 [Escherichia coli O157:H16]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References