Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 4011034..4011830 Replicon chromosome
Accession NZ_CP062821
Organism Providencia rettgeri strain Res13-Sevr-LER2-35

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag IMQ36_RS18655 Protein ID WP_195697803.1
Coordinates 4011034..4011546 (-) Length 171 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag IMQ36_RS18660 Protein ID WP_102138080.1
Coordinates 4011543..4011830 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IMQ36_RS18640 4007086..4008057 - 972 WP_195697802.1 DNA-binding transcriptional regulator DsdC -
IMQ36_RS18645 4008274..4009611 + 1338 WP_102138077.1 D-serine transporter DsdX -
IMQ36_RS18650 4009624..4010958 + 1335 WP_102138078.1 D-serine ammonia-lyase -
IMQ36_RS18655 4011034..4011546 - 513 WP_195697803.1 GNAT family N-acetyltransferase Toxin
IMQ36_RS18660 4011543..4011830 - 288 WP_102138080.1 DUF1778 domain-containing protein Antitoxin
IMQ36_RS18665 4012079..4013134 - 1056 WP_102138081.1 osmoprotectant NAGGN system M42 family peptidase -
IMQ36_RS18670 4013139..4013909 - 771 WP_102138082.1 FadR family transcriptional regulator -
IMQ36_RS18675 4013940..4014743 - 804 WP_166264184.1 ATP-binding cassette domain-containing protein -
IMQ36_RS18680 4014743..4016557 - 1815 WP_102138084.1 dipeptide/oligopeptide/nickel ABC transporter permease/ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(32-147)

Antitoxin

Vibrio phage ICP1, Orf50

(14-87)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 18279.13 Da        Isoelectric Point: 9.5982

>T176706 WP_195697803.1 NZ_CP062821:c4011546-4011034 [Providencia rettgeri]
MTLKLTAPEPLKTGHLLEGFSSGEEALDLWLKNRAMSNQNSGASRTFVTTSDNQVMGYYALSTGVVSTNQAVGRFRSNMP
SDIPVILLGRLAVDTRAKGLGVGRGLVKDACHRVIQASGLVGIRGVVVHALTDNAKRFYEHIGFVPSPLDSMMLMITLAD
LQFALGIHPN

Download         Length: 513 bp

>T176706 NZ_CP082909:5177875-5178180 [Endozoicomonas sp. 4G]
ATGATCACCATTAAAGAAACTGAGACCTACCGTAAGTGGGAGCGAAAGCTGAAGAATGCCCGGGCAAAAGCCATAATAGC
GGCCCGAGTATTTCGCTTGGCTAATGGCCTTCCTGGTGATGTTGCTCCGGTTGGCCAAGGGATCAGCGAACTTAGGGTTC
ATTACGGACCTGGATACCGGGTGTACTTTCGCCAACAAGGGAACGAAATCATTCTTTTGTTGTGTGGAGGGGACAAGAGT
ACTCAGAGCAAAGATATAGAGCTTGCTAAACAGCTGGCACAAGAATGGAGGAAAAGTGATGACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10607.97 Da        Isoelectric Point: 4.8660

>AT176706 WP_102138080.1 NZ_CP062821:c4011830-4011543 [Providencia rettgeri]
MSTQNDVAVTRSSLNLRIKPEDKILIDRAANAVGKNRTEFVLEAARRAAEETLADLRVINVSAEVYQEFISQLDAAPSSN
EALRKTMMSKSPWEE

Download         Length: 288 bp

>AT176706 NZ_CP082909:5178173-5178463 [Endozoicomonas sp. 4G]
ATGACTGAACCCGTATACACTTATGACCCCGCTGCGGCACTGGACAGCCCGGAAGCCCGGGAGGTGTTTATTGCTGATGC
TTTTGAGACTGGCGACGCTTCTTATATTGCTAAGGCGCTGGGAGTTGTTGCCCGGGCTGAGGGGATGAGCAATATTGCCA
GACAAACCGGACTTTCCCGAGAGCAACTGTATCGCTCATTCAGCGAAGATGGAAACCCAACACTGAAGACCATCTTGAAT
GTCATGAAGGCCTTGGGCTTTACCATCACCGCTACTAAAAATCTAACATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References