Detailed information of TA system TA176703

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 2161588..2162504
• Replicon: chromosome
• Accession: NZ_CP062821
• Organism: Providencia rettgeri strain Res13-Sevr-LER2-35

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: IMQ36_RS09890
• Protein ID: WP_195698679.1
• Coordinates: 2161588..2162046 (-)
• Length: 153 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: IMQ36_RS09895
• Protein ID: WP_195698680.1
• Coordinates: 2162043..2162504 (-)
• Length: 154 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
IMQ36_RS09865	2157128..2158594	+	1467	WP_195698677.1	AMP nucleosidase	-
IMQ36_RS09870	2158575..2159138	+	564	WP_102140350.1	GNAT family N-acetyltransferase	-
IMQ36_RS09875	2159169..2159591	+	423	WP_102140349.1	helix-turn-helix domain-containing protein	-
IMQ36_RS09880	2159696..2160655	+	960	WP_166267463.1	acetyl-CoA carboxylase carboxyl transferase subunit alpha	-
IMQ36_RS09885	2160697..2161587	+	891	WP_195698678.1	LysR family transcriptional regulator	-
IMQ36_RS09890	2161588..2162046	-	459	WP_195698679.1	RES domain-containing protein	Toxin
IMQ36_RS09895	2162043..2162504	-	462	WP_195698680.1	DUF2384 domain-containing protein	Antitoxin
IMQ36_RS09900	2162591..2163058	-	468	WP_102140344.1	DUF1456 family protein	-
IMQ36_RS09905	2163246..2163560	-	315	WP_102140343.1	AzlD domain-containing protein	-
IMQ36_RS09910	2163557..2164258	-	702	WP_102140342.1	AzlC family ABC transporter permease	-
IMQ36_RS09915	2164733..2165374	+	642	WP_195698681.1	leucine efflux protein LeuE	-
IMQ36_RS09920	2165635..2165901	+	267	WP_166267457.1	GntR family transcriptional regulator	-
IMQ36_RS09925	2165934..2166323	+	390	WP_195698682.1	cytidine deaminase	-
IMQ36_RS09930	2166380..2166853	+	474	WP_195698683.1	NUDIX domain-containing protein	-
IMQ36_RS09935	2166877..2167491	-	615	WP_195698684.1	LysE family translocator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-146)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (99-150)

Sequences

Toxin

Protein

• Length: 153 a.a.
• Molecular weight: 17109.67 Da
• Isoelectric Point: 5.9497

>T176703 WP_195698679.1 NZ_CP062821:c2162046-2161588 [Providencia rettgeri]
MILYRLVKSSFAHDAWSGQGAMLYGGRWNHKGTPAVYTSTSISLATLEILVHINQDILLNQFSLLSIDINDKYVMKLSLD
HLPTDWQQDPAPTSTMDIGTTWLNNQDSLVLLIPSCIIPYEYNAIINPLHPQFQKAIQTVKPLDFSVDPRLA

Nucleotide

• Length: 459 bp

>T176703 NZ_CP082909:c4900841-4900686 [Endozoicomonas sp. 4G]
ATGGAGGCGGCCGGCTGGAAGCTCGACAGGGTGAGAGGAAGCCACCACATTTTCAAACATCCAGATTTCAACAGATCAGT
ACCCATACCGCATCCCAAAAAGGATTTGAAGCAGGGAACATTGAAAGCAATCAGGAAGCAAGCCGGACTCATATAA

Antitoxin

Protein

• Length: 154 a.a.
• Molecular weight: 17026.51 Da
• Isoelectric Point: 9.7275

>AT176703 WP_195698680.1 NZ_CP062821:c2162504-2162043 [Providencia rettgeri]
MRNYIPTTPLQPAVSAFKPLWRHVGLPAERGIELTHYLRQGLSVSVLDNIQEWSGVSKAELLRISGINERNIARRKNAGQ
PLNADESERIARLVRVFDAAVRLFNGDKHAASDWLNHPVKGLGHLRPIELIATESGAIEVIDLIGRIEHGVFS

Nucleotide

• Length: 462 bp

>AT176703 NZ_CP082909:c4900620-4900219 [Endozoicomonas sp. 4G]
ATGAAATACCCAATTGCTATTGAGTGGGGTGACGATGAGCATGCCACTGGTATTGCAATACCTGACATACCGGGGGCAAT
CACGGCAGGGGATACCTACGAAGAAGCTTATAAGGGGGCCGTTGAGGTCGCTCATATTATGTTAGAGGAGATGGTTGGTA
ACGGTGAGGAGGTTCCTCTTCCATCTCCAGTGAAAGACTTGATGGTCAATCCGGATTATGAAGGATGGGGTTGGGGCCTG
ATCGAAGTAGATTTATCTCCTTACCTTGGGAAAACAGAAAAAATCAATGTCACGCTTCCCGGTGTACTGGTCAACAAAAT
TGACTCTTATGTAAAAAGTCACGACGTAAAAAGTCGATCAGCATTCCTGGCGGATGCAGCTATGGAAAAACTTCGCCTTT
AA