Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2354045..2354279 | Replicon | chromosome |
| Accession | NZ_CP062782 | ||
| Organism | Escherichia coli O157:H7 strain Z869 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2354175..2354278 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2354045..2354279 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ILQ35_RS11915 | 2350600..2351262 | - | 663 | WP_000944243.1 | exodeoxyribonuclease X | - |
| ILQ35_RS11920 | 2351286..2351942 | - | 657 | WP_000011656.1 | carbon-nitrogen hydrolase family protein | - |
| ILQ35_RS11925 | 2352044..2352274 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| ILQ35_RS11930 | 2352413..2352787 | + | 375 | WP_000168751.1 | CopC domain-containing protein YobA | - |
| ILQ35_RS11935 | 2352791..2353663 | + | 873 | WP_000879314.1 | copper homeostasis membrane protein CopD | - |
| ILQ35_RS11940 | 2353676..2354017 | + | 342 | WP_000976483.1 | YebY family protein | - |
| - | 2354045..2354279 | - | 235 | - | - | Antitoxin |
| - | 2354175..2354278 | + | 104 | - | - | Toxin |
| ILQ35_RS11945 | 2354410..2355486 | - | 1077 | WP_045893699.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| ILQ35_RS11950 | 2355452..2355733 | - | 282 | WP_001311878.1 | excisionase | - |
| ILQ35_RS11955 | 2355840..2356028 | - | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2355844..2356022 | + | 179 | NuclAT_0 | - | - |
| - | 2355844..2356022 | + | 179 | NuclAT_0 | - | - |
| - | 2355844..2356022 | + | 179 | NuclAT_0 | - | - |
| - | 2355844..2356022 | + | 179 | NuclAT_0 | - | - |
| ILQ35_RS11960 | 2356021..2356215 | - | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| ILQ35_RS11965 | 2356272..2357081 | - | 810 | WP_000166313.1 | recombination protein RecT | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2346635..2409305 | 62670 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T176571 NZ_CP062782:2354175-2354278 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT176571 NZ_CP062782:c2354279-2354045 [Escherichia coli O157:H7]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
