Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2315606..2315877 Replicon chromosome
Accession NZ_CP062749
Organism Escherichia coli O157:H7 strain Z1486

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2315736..2315839 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2315606..2315877 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ41_RS11650 2312161..2312823 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ41_RS11655 2312847..2313503 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ41_RS11660 2313605..2313835 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ41_RS11665 2313974..2314348 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ41_RS11670 2314352..2315224 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ41_RS11675 2315237..2315578 + 342 WP_000976483.1 YebY family protein -
- 2315606..2315877 - 272 - - Antitoxin
- 2315736..2315839 + 104 - - Toxin
ILQ41_RS11680 2315974..2316630 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ41_RS11685 2316631..2316822 - 192 WP_001296140.1 YebW family protein -
ILQ41_RS11690 2316927..2317163 - 237 WP_001295499.1 DUF1480 family protein -
ILQ41_RS11695 2317281..2318720 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T176135 NZ_CP062749:2315736-2315839 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT176135 NZ_CP062749:c2315877-2315606 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References