Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2317001..2317272 Replicon chromosome
Accession NZ_CP062721
Organism Escherichia coli O157:H7 strain Z1815

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2317131..2317234 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2317001..2317272 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ54_RS11665 2313556..2314218 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ54_RS11670 2314242..2314898 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ54_RS11675 2315000..2315230 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ54_RS11680 2315369..2315743 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ54_RS11685 2315747..2316619 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ54_RS11690 2316632..2316973 + 342 WP_000976483.1 YebY family protein -
- 2317001..2317272 - 272 - - Antitoxin
- 2317131..2317234 + 104 - - Toxin
ILQ54_RS11695 2317369..2318025 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ54_RS11700 2318026..2318217 - 192 WP_001296140.1 YebW family protein -
ILQ54_RS11705 2318322..2318558 - 237 WP_001295499.1 DUF1480 family protein -
ILQ54_RS11710 2318676..2320115 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T175695 NZ_CP062721:2317131-2317234 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT175695 NZ_CP062721:c2317272-2317001 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References