Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2363226..2363497 Replicon chromosome
Accession NZ_CP062713
Organism Escherichia coli O157:H7 strain Z1830

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2363356..2363459 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2363226..2363497 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ILQ58_RS11950 2359781..2360443 - 663 WP_000944243.1 exodeoxyribonuclease X -
ILQ58_RS11955 2360467..2361123 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
ILQ58_RS11960 2361225..2361455 - 231 WP_000916763.1 DNA polymerase III subunit theta -
ILQ58_RS11965 2361594..2361968 + 375 WP_000168751.1 CopC domain-containing protein YobA -
ILQ58_RS11970 2361972..2362844 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
ILQ58_RS11975 2362857..2363198 + 342 WP_000976483.1 YebY family protein -
- 2363226..2363497 - 272 - - Antitoxin
- 2363356..2363459 + 104 - - Toxin
ILQ58_RS11980 2363594..2364250 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
ILQ58_RS11985 2364251..2364442 - 192 WP_001296140.1 YebW family protein -
ILQ58_RS11990 2364547..2364783 - 237 WP_001295499.1 DUF1480 family protein -
ILQ58_RS11995 2364901..2366340 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T175551 NZ_CP062713:2363356-2363459 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT175551 NZ_CP062713:c2363497-2363226 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References