Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 775158..775809 Replicon chromosome
Accession NZ_CP062698
Organism Anthocerotibacter panamensis C109

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag IL331_RS03570 Protein ID WP_218081760.1
Coordinates 775158..775568 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag IL331_RS03575 Protein ID WP_218081761.1
Coordinates 775570..775809 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IL331_RS03560 773776..774102 + 327 WP_218081758.1 hypothetical protein -
IL331_RS03565 774210..775061 + 852 WP_218081759.1 hypothetical protein -
IL331_RS03570 775158..775568 - 411 WP_218081760.1 type II toxin-antitoxin system VapC family toxin Toxin
IL331_RS03575 775570..775809 - 240 WP_218081761.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
IL331_RS03585 776851..778056 + 1206 WP_218081763.1 glycosyltransferase -
IL331_RS03590 778040..779149 + 1110 WP_218081764.1 glycosyltransferase family 1 protein -
IL331_RS03595 779162..780655 + 1494 WP_218081765.1 radical SAM protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-126)

Antitoxin

SpoVT-AbrB domain

(10-54)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15263.82 Da        Isoelectric Point: 6.7202

>T175347 WP_218081760.1 NZ_CP062698:c775568-775158 [Anthocerotibacter panamensis C109]
MEDIRYLLDTNIVSDLIKHPAGRVVQHIKTKGEDTLAISIVVACELRFGAAKKNVPILSTKIEQLLSSLKIFPLTVDADR
YYADLRVYLENNGTPIGPNDMLIASHALALDLILVTANIREFSRIPRLKVENWLEP

Download         Length: 411 bp

>T175347 NZ_CP081891:c2670154-2668832 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCGGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGAGAGCAGATGTTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9140.57 Da        Isoelectric Point: 4.8177

>AT175347 WP_218081761.1 NZ_CP062698:c775809-775570 [Anthocerotibacter panamensis C109]
MHPERHIRLFRNGRNQALRIPREFQLPGNEAIIRKEGDRLIIEPVPRPALLALLATWEPVAEEFPNIDEALIPIDDIDL

Download         Length: 240 bp

>AT175347 NZ_CP081891:c2670420-2670154 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGATGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References