Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2193861..2194132 Replicon chromosome
Accession NZ_CP061749
Organism Escherichia coli O15:H12 strain 2273-PO3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2193991..2194094 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2193861..2194132 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IED00_RS10485 2190416..2191078 - 663 WP_000944256.1 exodeoxyribonuclease X -
IED00_RS10490 2191102..2191758 - 657 WP_000011660.1 carbon-nitrogen hydrolase family protein -
IED00_RS10495 2191860..2192090 - 231 WP_000916763.1 DNA polymerase III subunit theta -
IED00_RS10500 2192229..2192603 + 375 WP_000168738.1 CopC domain-containing protein YobA -
IED00_RS10505 2192607..2193479 + 873 WP_000879286.1 copper homeostasis membrane protein CopD -
IED00_RS10510 2193492..2193833 + 342 WP_000976472.1 YebY family protein -
- 2193861..2194132 - 272 - - Antitoxin
- 2193991..2194094 + 104 - - Toxin
IED00_RS10515 2194229..2194885 + 657 WP_000812740.1 protein-serine/threonine phosphatase -
IED00_RS10520 2194886..2195077 - 192 WP_001313035.1 YebW family protein -
IED00_RS10525 2195182..2195418 - 237 WP_001295499.1 DUF1480 family protein -
IED00_RS10530 2195536..2196975 - 1440 WP_001383086.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T172876 NZ_CP061749:2193991-2194094 [Escherichia coli O15:H12]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT172876 NZ_CP061749:c2194132-2193861 [Escherichia coli O15:H12]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References