Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2494756..2494989 Replicon chromosome
Accession NZ_CP061527
Organism Shigella dysenteriae strain HNCMB 20080

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2494756..2494859 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2494756..2494989 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IC625_RS13235 2490520..2490639 - 120 WP_001131442.1 hypothetical protein -
IC625_RS13240 2490600..2490785 - 186 WP_023637031.1 hypothetical protein -
IC625_RS13250 2491823..2492104 + 282 WP_194947008.1 excisionase -
IC625_RS13255 2492219..2492915 - 697 Protein_2592 IS1 family transposase -
IC625_RS13260 2492992..2494148 + 1157 WP_134801760.1 IS3-like element IS600 family transposase -
IC625_RS13265 2494194..2494634 + 441 Protein_2594 tyrosine-type recombinase/integrase -
- 2494756..2494859 - 104 - - Toxin
- 2494756..2494989 + 234 - - Antitoxin
IC625_RS13270 2495017..2495358 - 342 WP_134802023.1 YebY family protein -
IC625_RS13275 2495371..2496243 - 873 WP_000879288.1 copper homeostasis membrane protein CopD -
IC625_RS13280 2496247..2496621 - 375 WP_000168738.1 CopC domain-containing protein YobA -
IC625_RS13285 2496760..2496990 + 231 WP_000916763.1 DNA polymerase III subunit theta -
IC625_RS13290 2497092..2497748 + 657 WP_000896381.1 carbon-nitrogen hydrolase family protein -
IC625_RS13295 2497772..2498434 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T172694 NZ_CP061527:c2494859-2494756 [Shigella dysenteriae]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 234 bp

>AT172694 NZ_CP061527:2494756-2494989 [Shigella dysenteriae]
AAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATA
AAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGTTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References