Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1848294..1848439 Replicon chromosome
Accession NZ_CP061380
Organism Klebsiella pneumoniae strain NU-CRE236

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1848330..1848432 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1848294..1848439 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HCV86_RS08905 1843424..1845484 + 2061 WP_004151449.1 oligopeptidase B -
HCV86_RS08910 1845488..1846147 - 660 WP_002911407.1 exodeoxyribonuclease X -
HCV86_RS08915 1846226..1846456 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HCV86_RS08920 1846569..1846943 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HCV86_RS08925 1846947..1847816 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HCV86_RS08930 1847833..1848171 + 339 WP_004189269.1 YebY family protein -
- 1848294..1848439 - 146 - - Antitoxin
- 1848330..1848432 + 103 - - Toxin
HCV86_RS08935 1848806..1848949 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HCV86_RS08940 1849054..1850022 - 969 WP_004151446.1 VirK/YbjX family protein -
HCV86_RS08945 1850179..1850832 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
HCV86_RS08950 1850829..1851020 - 192 WP_002911395.1 YebW family protein -
HCV86_RS08955 1851118..1851357 - 240 WP_002911393.1 YebV family protein -
HCV86_RS08960 1851473..1852906 - 1434 WP_167580712.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T172535 NZ_CP061380:1848330-1848432 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT172535 NZ_CP061380:c1848439-1848294 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References