172044

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 2503677..2505427 Replicon chromosome
Accession NZ_CP061081
Organism Marinomonas arctica strain BSI20414

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag IBG28_RS11575 Protein ID WP_188322892.1
Coordinates 2503677..2504330 (+) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag IBG28_RS11580 Protein ID WP_111607316.1
Coordinates 2504327..2505427 (+) Length 367 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IBG28_RS11545 2499189..2499509 + 321 WP_111607323.1 hypothetical protein -
IBG28_RS11550 2499603..2500025 + 423 WP_111607322.1 VOC family protein -
IBG28_RS11555 2500146..2500775 + 630 WP_111607321.1 OmpA family protein -
IBG28_RS11560 2501038..2502051 + 1014 WP_111607320.1 NAD(P)-dependent alcohol dehydrogenase -
IBG28_RS11565 2502317..2502922 + 606 WP_111607319.1 Fic family protein -
IBG28_RS11570 2503106..2503684 + 579 WP_111607318.1 DUF4433 domain-containing protein -
IBG28_RS11575 2503677..2504330 + 654 WP_188322892.1 DUF4433 domain-containing protein Toxin
IBG28_RS11580 2504327..2505427 + 1101 WP_111607316.1 macro domain-containing protein Antitoxin
IBG28_RS11585 2505709..2505870 - 162 WP_188322893.1 hypothetical protein -
IBG28_RS11590 2506121..2506603 - 483 WP_111607315.1 hypothetical protein -
IBG28_RS11595 2506603..2507310 - 708 WP_111607314.1 DUF3800 domain-containing protein -
IBG28_RS11600 2507326..2507892 - 567 WP_111607313.1 restriction endonuclease subunit S -
IBG28_RS11605 2507829..2509101 - 1273 Protein_2277 restriction endonuclease subunit S -
IBG28_RS11610 2509104..2510168 - 1065 WP_111607355.1 DUF1016 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-216)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 25436.07 Da        Isoelectric Point: 7.1581

>T172044 WP_188322892.1 NZ_CP061081:2503677-2504330 [Marinomonas arctica]
MTNHYPNLNPEKALIWRIVHRDNLAWILDNGLHCASSQKVAEHYEPIGNTDLIHKRTQRNVPIKPYGTLSDYIPFYFTPF
SPMMYNIHTGRGGVKQRANEEIVILVSSIPKLIDSKVPFVFTDRHAYTAFAEFFDNSDELIKLDWTIIQQRNFQRNQDDP
AQIERYQAEALVYKHCPITSLLGIVCYSDEMKQQLEQIVKEKSLAIDVRKMTQWYFQ

Download         Length: 654 bp

>T172044 NZ_CP079164:4706505-4707827 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCACCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACTCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 367 a.a.        Molecular weight: 41892.97 Da        Isoelectric Point: 5.8988

>AT172044 WP_111607316.1 NZ_CP061081:2504327-2505427 [Marinomonas arctica]
MIHYTQGNLLEADVDALVNTVNTVGVMGKGIALMFKERFPKNTQDYANACKAKQVETGRMFVTQTGELVGPRWIVNFPTK
RHWRNPSKLEWITEGLVDLKQVILDNHLNSIAIPALGAGNGKLNWESVKPEIERILGDLESVDILVFEPTQRYQNVAKQK
GHTKLTPARAMIAELIRQYWVMGMECTLLEVQKLAWFLERSIEKHNGSNKTDNPLDLRFEANLYGPYADRLRHLIDHLDG
IYLYCNKRINDAEPLDVIWFEDSKQDQLNTYLKSAEMAPYLTSLQDTIELIDGFETPFGMELLSTIDWLVSKENIEPDLQ
KIIQGIQHWPAGEASAKRKTNLFDERSINIALNRLKNTYQPLIQNA

Download         Length: 1101 bp

>AT172044 NZ_CP079164:4706239-4706505 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGATGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References