Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 1758373..1758915 Replicon chromosome
Accession NZ_CP061081
Organism Marinomonas arctica strain BSI20414

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IBG28_RS08040 Protein ID WP_111606152.1
Coordinates 1758373..1758642 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IBG28_RS08045 Protein ID WP_111606151.1
Coordinates 1758649..1758915 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IBG28_RS08015 1754118..1754783 - 666 WP_111606156.1 LysE family translocator -
IBG28_RS08020 1754865..1755779 + 915 WP_111606220.1 LysR family transcriptional regulator -
IBG28_RS08025 1756030..1757016 + 987 WP_111606155.1 alpha/beta hydrolase -
IBG28_RS08030 1757091..1757504 + 414 WP_111606154.1 gamma-glutamylcyclotransferase -
IBG28_RS08035 1757519..1758076 - 558 WP_111606153.1 DNA-binding protein -
IBG28_RS08040 1758373..1758642 - 270 WP_111606152.1 type II toxin-antitoxin system YafQ family toxin Toxin
IBG28_RS08045 1758649..1758915 - 267 WP_111606151.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
IBG28_RS08050 1759244..1760497 + 1254 WP_111606150.1 sarcosine oxidase subunit beta family protein -
IBG28_RS08055 1760530..1760823 + 294 WP_111606149.1 sarcosine oxidase subunit delta -
IBG28_RS08060 1760836..1763868 + 3033 WP_111606148.1 sarcosine oxidase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(3-84)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10253.96 Da        Isoelectric Point: 9.5518

>T172042 WP_111606152.1 NZ_CP061081:c1758642-1758373 [Marinomonas arctica]
MYQLVYSTQFKKDFKKITKMPIADIIEVGNIISRLQRGESLDTKHVNHPLTGNWLGFKDCHIKPDLVLIYRVIDNALQLA
RIGSHSDVF

Download         Length: 270 bp

>T172042 NZ_CP079164:c3369914-3369696 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9743.11 Da        Isoelectric Point: 6.4777

>AT172042 WP_111606151.1 NZ_CP061081:c1758915-1758649 [Marinomonas arctica]
MKNEMLSTRIDHETKAAFTHICDEVGLSPSQAIKLFAKAVINHGGIPFDIKMRQPNTDTIAAMKELNQGQGHKAESVSSM
FEELTEAR

Download         Length: 267 bp

>AT172042 NZ_CP079164:c3370315-3369941 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References