Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2086086..2086357 Replicon chromosome
Accession NZ_CP060709
Organism Escherichia coli strain ST18

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2086124..2086227 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2086086..2086357 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H9445_RS10505 2083243..2084682 + 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
H9445_RS10510 2084800..2085036 + 237 WP_001295499.1 DUF1480 family protein -
H9445_RS10515 2085141..2085332 + 192 WP_000457842.1 YebW family protein -
H9445_RS10520 2085333..2085989 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 2086086..2086357 + 272 - - Antitoxin
- 2086124..2086227 - 104 - - Toxin
H9445_RS10525 2086385..2086726 - 342 WP_000976476.1 YebY family protein -
H9445_RS10530 2086739..2087611 - 873 WP_000879289.1 copper homeostasis membrane protein CopD -
H9445_RS10535 2087615..2087989 - 375 WP_000168747.1 CopC domain-containing protein YobA -
H9445_RS10540 2088128..2088358 + 231 WP_000916763.1 DNA polymerase III subunit theta -
H9445_RS10545 2088460..2089116 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H9445_RS10550 2089140..2089802 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T170823 NZ_CP060709:c2086227-2086124 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT170823 NZ_CP060709:2086086-2086357 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References