Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018948..2019219 Replicon chromosome
Accession NZ_CP060065
Organism Escherichia coli strain G5

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2019078..2019181 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018948..2019219 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4P49_RS09660 2015503..2016165 - 663 WP_001556661.1 exodeoxyribonuclease X -
H4P49_RS09665 2016189..2016845 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
H4P49_RS09670 2016947..2017177 - 231 WP_000916763.1 DNA polymerase III subunit theta -
H4P49_RS09675 2017316..2017690 + 375 WP_000168747.1 CopC domain-containing protein YobA -
H4P49_RS09680 2017694..2018566 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
H4P49_RS09685 2018579..2018920 + 342 WP_000976472.1 YebY family protein -
- 2018948..2019219 - 272 - - Antitoxin
- 2019078..2019181 + 104 - - Toxin
H4P49_RS09690 2019316..2019972 + 657 WP_000812732.1 protein-serine/threonine phosphatase -
H4P49_RS09695 2019973..2020164 - 192 WP_001338167.1 YebW family protein -
H4P49_RS09700 2020269..2020505 - 237 WP_001338166.1 DUF1480 family protein -
H4P49_RS09705 2020623..2022062 - 1440 WP_001351758.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T169841 NZ_CP060065:2019078-2019181 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT169841 NZ_CP060065:c2019219-2018948 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References