Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 1817376..1817959 Replicon chromosome
Accession NZ_CP059958
Organism Pectobacterium brasiliense strain IPO:4065 NAK:223

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H5A29_RS07950 Protein ID WP_119871112.1
Coordinates 1817376..1817681 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A29_RS07955 Protein ID WP_119871111.1
Coordinates 1817669..1817959 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A29_RS07935 1813792..1814751 + 960 WP_039279295.1 ABC transporter permease -
H5A29_RS07940 1814744..1815610 + 867 WP_010285293.1 ABC transporter permease -
H5A29_RS07945 1815607..1817316 + 1710 WP_119871113.1 ABC transporter ATP-binding protein -
H5A29_RS07950 1817376..1817681 - 306 WP_119871112.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A29_RS07955 1817669..1817959 - 291 WP_119871111.1 ribbon-helix-helix protein, CopG family Antitoxin
H5A29_RS07960 1818021..1818875 - 855 WP_119871110.1 helix-turn-helix domain-containing protein -
H5A29_RS07965 1818900..1819739 - 840 WP_014913998.1 HTH-type transcriptional activator RhaS -
H5A29_RS07970 1820076..1821566 + 1491 WP_119871109.1 rhamnulokinase -
H5A29_RS07975 1821563..1822825 + 1263 WP_039282588.1 L-rhamnose isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11602.42 Da        Isoelectric Point: 9.4590

>T169547 WP_119871112.1 NZ_CP059958:c1817681-1817376 [Pectobacterium brasiliense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVVLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T169547 NZ_CP076591:c573299-573120 [Erwinia amylovora]
ATGGATAGCAGGAATGCAATAGCAATGATAGAGGCCGATGGATGGTATCTGGTGAGAGTAAAAGGCAGTCATCACCAGTT
CAAGCACCCAACGAAAAAAGGGCTGGTAACGGTAAAACATCCCCAAAAGGACATACCGCTACCAACGCTGAAAAGCATTA
AAAAACAGGCGGGGCTTTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11100.17 Da        Isoelectric Point: 4.7845

>AT169547 WP_119871111.1 NZ_CP059958:c1817959-1817669 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAITEYVEREEKRSQYRKEALAAWEEYQSTGEHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT169547 NZ_CP076591:c573097-572687 [Erwinia amylovora]
ATGTTATACCCTGTTGCTATTGATAAAGGCGATTCATCCTTCGGCGTTCGCGTACCCGATATTCCAGGCTGCTTCTCTGG
CGGCGACAATTATCAGGATGCGATTGAGAGCGCGCGTGAGGCTATCGACGCGCATATCGAATTACTGGTGGAAGATGGCG
AAGCGGTGCCGGAAGCGACCAGCGTGGAAAACTGGCTGGCCGATCCCGATTATGTTGGTGTGGTGTGGGCGCTGGTAGAT
GTGGACGTTACCCGGCTGATGGGGAAAGCGGAAAAAATCAATGTTACGCTCCCTTCTTTACTGATCCGCCGTATCGATCA
GTTTGTCGCTGCACATCCTGAGTACGGTAGCCGTTCCGGCTTCCTGTCCCGCGTGGCGGCTGATAAAGTGATTGGTCGCG
AAAAACGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References