Detailed information of TA system TA169547

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1817376..1817959
• Replicon: chromosome
• Accession: NZ_CP059958
• Organism: Pectobacterium brasiliense strain IPO:4065 NAK:223

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: H5A29_RS07950
• Protein ID: WP_119871112.1
• Coordinates: 1817376..1817681 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: H5A29_RS07955
• Protein ID: WP_119871111.1
• Coordinates: 1817669..1817959 (-)
• Length: 97 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
H5A29_RS07935	1813792..1814751	+	960	WP_039279295.1	ABC transporter permease	-
H5A29_RS07940	1814744..1815610	+	867	WP_010285293.1	ABC transporter permease	-
H5A29_RS07945	1815607..1817316	+	1710	WP_119871113.1	ABC transporter ATP-binding protein	-
H5A29_RS07950	1817376..1817681	-	306	WP_119871112.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
H5A29_RS07955	1817669..1817959	-	291	WP_119871111.1	ribbon-helix-helix protein, CopG family	Antitoxin
H5A29_RS07960	1818021..1818875	-	855	WP_119871110.1	helix-turn-helix domain-containing protein	-
H5A29_RS07965	1818900..1819739	-	840	WP_014913998.1	HTH-type transcriptional activator RhaS	-
H5A29_RS07970	1820076..1821566	+	1491	WP_119871109.1	rhamnulokinase	-
H5A29_RS07975	1821563..1822825	+	1263	WP_039282588.1	L-rhamnose isomerase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-96)

Antitoxin

• Ribbon-helix-helix protein, CopG (9-46)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 11602.42 Da
• Isoelectric Point: 9.4590

>T169547 WP_119871112.1 NZ_CP059958:c1817681-1817376 [Pectobacterium brasiliense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVVLYRHDE
LTDRVVILTVKHQKEAGYQNP

Nucleotide

• Length: 306 bp

>T169547 NZ_CP076591:c573299-573120 [Erwinia amylovora]
ATGGATAGCAGGAATGCAATAGCAATGATAGAGGCCGATGGATGGTATCTGGTGAGAGTAAAAGGCAGTCATCACCAGTT
CAAGCACCCAACGAAAAAAGGGCTGGTAACGGTAAAACATCCCCAAAAGGACATACCGCTACCAACGCTGAAAAGCATTA
AAAAACAGGCGGGGCTTTAA

Antitoxin

Protein

• Length: 97 a.a.
• Molecular weight: 11100.17 Da
• Isoelectric Point: 4.7845

>AT169547 WP_119871111.1 NZ_CP059958:c1817959-1817669 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAITEYVEREEKRSQYRKEALAAWEEYQSTGEHITADETVTWL
ESWGSGHEQDAPACHK

Nucleotide

• Length: 291 bp

>AT169547 NZ_CP076591:c573097-572687 [Erwinia amylovora]
ATGTTATACCCTGTTGCTATTGATAAAGGCGATTCATCCTTCGGCGTTCGCGTACCCGATATTCCAGGCTGCTTCTCTGG
CGGCGACAATTATCAGGATGCGATTGAGAGCGCGCGTGAGGCTATCGACGCGCATATCGAATTACTGGTGGAAGATGGCG
AAGCGGTGCCGGAAGCGACCAGCGTGGAAAACTGGCTGGCCGATCCCGATTATGTTGGTGTGGTGTGGGCGCTGGTAGAT
GTGGACGTTACCCGGCTGATGGGGAAAGCGGAAAAAATCAATGTTACGCTCCCTTCTTTACTGATCCGCCGTATCGATCA
GTTTGTCGCTGCACATCCTGAGTACGGTAGCCGTTCCGGCTTCCTGTCCCGCGTGGCGGCTGATAAAGTGATTGGTCGCG
AAAAACGTTAA