Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 106241..106824 Replicon chromosome
Accession NZ_CP059957
Organism Pectobacterium brasiliense strain IPO:4071 NAK:240

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H5A30_RS00520 Protein ID WP_119871112.1
Coordinates 106241..106546 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag H5A30_RS00525 Protein ID WP_119871111.1
Coordinates 106534..106824 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H5A30_RS00505 102657..103616 + 960 WP_039279295.1 ABC transporter permease -
H5A30_RS00510 103609..104475 + 867 WP_010285293.1 ABC transporter permease -
H5A30_RS00515 104472..106181 + 1710 WP_119871113.1 ABC transporter ATP-binding protein -
H5A30_RS00520 106241..106546 - 306 WP_119871112.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H5A30_RS00525 106534..106824 - 291 WP_119871111.1 ribbon-helix-helix protein, CopG family Antitoxin
H5A30_RS00530 106886..107740 - 855 WP_119871110.1 helix-turn-helix domain-containing protein -
H5A30_RS00535 107765..108604 - 840 WP_014913998.1 HTH-type transcriptional activator RhaS -
H5A30_RS00540 108941..110431 + 1491 WP_119871109.1 rhamnulokinase -
H5A30_RS00545 110428..111690 + 1263 WP_039282588.1 L-rhamnose isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-96)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11602.42 Da        Isoelectric Point: 9.4590

>T169525 WP_119871112.1 NZ_CP059957:c106546-106241 [Pectobacterium brasiliense]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVVLYRHDE
LTDRVVILTVKHQKEAGYQNP

Download         Length: 306 bp

>T169525 NZ_CP076545:241722-242000 [Collinsella sp. zg1085]
ATGTTAGAGCTTCGCGCGACATCCAAGTTTCGCAAGGACTATAAGCGCATCGAGAAACGCGGCTATAATTTGGCTTTGCT
TGAAGCGGTTCTGGAAAAGCTTCTCAACCAAGAACCGTTAGAAGCAAGGTATAAAGACCATGCCCTCACCGGCTCCTACG
CAGGCTTTAGAGAATGTCATATCCAGCCTGACTGGCTTTTTATCTATGCGGTCGAAAAAGACCAGCTCATTCTTGTTGCT
GCCGGCACAGGCACACATGCCGATTTATTCAACATGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11100.17 Da        Isoelectric Point: 4.7845

>AT169525 WP_119871111.1 NZ_CP059957:c106824-106534 [Pectobacterium brasiliense]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAITEYVEREEKRSQYRKEALAAWEEYQSTGEHITADETVTWL
ESWGSGHEQDAPACHK

Download         Length: 291 bp

>AT169525 NZ_CP076545:241429-241719 [Collinsella sp. zg1085]
TTGGCTAAAACAGCAAATATCAATCTCAGGATCGAACCTCAGGTCAAACGGGATGCTGAGGCGATTTTTGAAAGCTTTGG
GATTTCGGTTACTGATGCGATTAACATCTTTTTGCATCAGTCCATCATGGAGCAGGGTTTTCCGTTTGCGATTCAGCGTC
CCAGATATAACGCAGAAACCGAAGCAGCTCTGCAAGAAGCACGCGATATTCTTTCAGGAAAGATTCCAGCCAAGTCGTAT
GGTTCAGCCAGAGAGCTCTTTGCTGACTTGGATCTGGAAGCTGAAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References