Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2731775..2733228 Replicon chromosome
Accession NZ_CP059710
Organism Xanthomonas oryzae pv. oryzicola strain ML5

Toxin (Protein)


Gene name rlegT Uniprot ID A0A5C2EYQ5
Locus tag H4J00_RS12485 Protein ID WP_047339759.1
Coordinates 2731775..2732626 (-) Length 284 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A0C5V250
Locus tag H4J00_RS12490 Protein ID WP_024710981.1
Coordinates 2732623..2733228 (-) Length 202 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H4J00_RS12460 (H4J00_12410) 2726815..2727777 - 963 WP_044751530.1 IS110 family transposase -
H4J00_RS12465 (H4J00_12415) 2728002..2728304 - 303 WP_048485513.1 hypothetical protein -
H4J00_RS12470 (H4J00_12420) 2729177..2729518 - 342 WP_050585837.1 ParB N-terminal domain-containing protein -
H4J00_RS12475 (H4J00_12425) 2729515..2730801 - 1287 WP_218639763.1 recombinase family protein -
H4J00_RS12480 (H4J00_12430) 2731218..2731688 - 471 WP_047339760.1 hypothetical protein -
H4J00_RS12485 (H4J00_12435) 2731775..2732626 - 852 WP_047339759.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
H4J00_RS12490 (H4J00_12440) 2732623..2733228 - 606 WP_024710981.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
H4J00_RS12495 (H4J00_12445) 2733472..2734257 - 786 WP_053056035.1 helix-turn-helix domain-containing protein -
H4J00_RS12500 (H4J00_12450) 2734583..2734759 + 177 WP_014503024.1 hypothetical protein -
H4J00_RS12505 (H4J00_12455) 2735066..2736151 + 1086 WP_048485514.1 sensor domain-containing diguanylate cyclase -
H4J00_RS12510 (H4J00_12460) 2736194..2736703 - 510 WP_014503022.1 chemotaxis protein CheW -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2713707..2741513 27806
flank IS/Tn - - 2726815..2727777 962


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(34-262)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-55)


Sequences

Toxin        


Download         Length: 284 a.a.        Molecular weight: 31056.91 Da        Isoelectric Point: 7.0657

>T169064 WP_047339759.1 NZ_CP059710:c2732626-2731775 [Xanthomonas oryzae pv. oryzicola]
MSNVAASVRARLRGVAKAQGVDFNQVLVRFALERILYRLSQSEHADRFLLKGALLFTLWYDMPHRATRDADLLGFGASDL
ESVAQTFRDIASVAVDDGIVFDPASVVAEEIRKDAGYAGARILIGGELAKARCRTQIDVGFGDAVTPAPVHSVYPVLLED
LPAPRLRTYPVYTVIAEKLHAIALLGMTNSRMKDYLDLSVLLERESLDIDLLAQAVKATFERRGMAVPAALPIGMTDEFA
HDTSRQALWQAFLKKNELAPEPLAAIVVRLRAALEPALHRAAR

Download         Length: 852 bp

>T169064 NZ_CP076274:c3147172-3146837 [Escherichia coli]
ATGATAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTATACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin


Download         Length: 202 a.a.        Molecular weight: 22257.92 Da        Isoelectric Point: 9.9253

>AT169064 WP_024710981.1 NZ_CP059710:c2733228-2732623 [Xanthomonas oryzae pv. oryzicola]
MLSDTHTQRVLDLASQKGLLRASDLDAINAPRVVLTRLTAAGVLERVGRGLYRLPDAQGSEFESLAAIATKVPQAVFCLL
TALQFHELTTQLPRQIWIAMPRGSHAPRIGYPPVKMVQMTGDVYAAGIEEHLRDGVRLRVYGAAKTVVDCFKHRNKIGLD
VALEALKDVRAKRKATADDLWRFATVCRVANVMRPYLEAVE

Download         Length: 606 bp

>AT169064 NZ_CP076274:c3147420-3147172 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5C2EYQ5

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V250

References