Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 381859..382680 Replicon plasmid pAR1aA
Accession NZ_CP059091
Organism Pantoea agglomerans strain AR1a

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag H0Z11_RS22700 Protein ID WP_208003304.1
Coordinates 381859..382329 (-) Length 157 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag H0Z11_RS22705 Protein ID WP_208003305.1
Coordinates 382336..382680 (-) Length 115 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H0Z11_RS22690 (H0Z11_22685) 377183..379585 + 2403 WP_208003302.1 maltodextrin phosphorylase -
H0Z11_RS22695 (H0Z11_22690) 379594..381669 + 2076 WP_208003303.1 4-alpha-glucanotransferase -
H0Z11_RS22700 (H0Z11_22695) 381859..382329 - 471 WP_208003304.1 type II toxin-antitoxin system YhaV family toxin Toxin
H0Z11_RS22705 (H0Z11_22700) 382336..382680 - 345 WP_208003305.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
H0Z11_RS22710 (H0Z11_22705) 382780..382995 - 216 WP_033780170.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
H0Z11_RS22715 (H0Z11_22710) 383184..384122 - 939 WP_208003306.1 maltose operon protein MalM -
H0Z11_RS22720 (H0Z11_22715) 384225..385526 - 1302 WP_208003307.1 maltoporin -
H0Z11_RS22725 (H0Z11_22720) 385570..386679 - 1110 WP_208003308.1 maltose/maltodextrin ABC transporter ATP-binding protein MalK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..557771 557771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-148)

Antitoxin

SpoVT-AbrB domain

(16-55)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 18195.73 Da        Isoelectric Point: 8.2687

>T168259 WP_208003304.1 NZ_CP059091:c382329-381859 [Pantoea agglomerans]
MEDSTVINGWHVYVHPCFESQLIALTNEVELLRAKYPESYQRKATTKLLAAVFKVINSEICADPHQAKFRQGDTLGEQNK
HWFRAKFLMQYRLFFRFSEQHKAIILAWMNDAETKCAYGSKRDAYKVFSGMLHNGYPPDDWALLLKQSQDWANTNS

Download         Length: 471 bp

>T168259 NZ_CP075686:5700024-5700206 [Pseudomonas amygdali pv. lachrymans]
ATGAAGTGCAACGAGTTTCGGCGATGGTTGCAGGCTCAAGGCGCTGAGTTCAGGGCTGCCAAGGGTAGTCATTTCAAGAT
TTACCTGAATGGTAAGGCAACCATCTTTGCAGACCATGGAAGCAAAGAAATGCACGAAGGGTTACGCAAGTCGATCATCA
AGCAGCTCGGCCTTAAGGATTGA

Antitoxin


Download         Length: 115 a.a.        Molecular weight: 12346.08 Da        Isoelectric Point: 4.7969

>AT168259 WP_208003305.1 NZ_CP059091:c382680-382336 [Pantoea agglomerans]
MGTLTHANISLRASSKLTARGQTTIPAAVRDAMNLQPGENIEYAVLQGGKVLITRQETMADDAQVKASFLSFLPADRRNT
AANIKMLDRGLLTRITSLTEGMDVDLDAPLMDDE

Download         Length: 345 bp

>AT168259 NZ_CP075686:5700238-5700663 [Pseudomonas amygdali pv. lachrymans]
ATGTATCAATATCCATTGGATCTACATCGGGAGCCGACAGGCGTTTGGCTGTCGTGTCCAGACATTCCCGAAATGAGCGC
CTCTGGCGACACCCTGCCTGAAGCATTTAGCGAAGCTCTTGACGGCATGGAATCGGCTCTATCGCTCTACGTCGATCAGC
GTCGCAAGATTCCCCAAGCCTCAGTCGTACCCGGCCATGAACTGTTGATGCGTTTGCCTGCGCTGACGGTTGCCAAAATC
ATGCTATGGAACAGCTTGTTGGAAGAGGGCGTTAGCCGTGCTGAGCTGGCGCGTCGCCTCGGTTGCACGCGGCAAGTGGT
GGATCGGCTTGTGGACTTTCTGCATGCCTCGAAAATCGAGCAGGTGGAGCGAGCGCTGGCTGAGCTTGGTCGGCGTATTA
CGTTGAGCATTGAGCGGGCCGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References