Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4160666..4161320 Replicon chromosome
Accession NZ_CP058644
Organism Pseudomonas yamanorum strain GZD14026

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag HZF02_RS19095 Protein ID WP_179451113.1
Coordinates 4160666..4161016 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HZF02_RS19100 Protein ID WP_155583981.1
Coordinates 4161006..4161320 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZF02_RS19085 4157423..4158955 + 1533 WP_155583984.1 NADH-quinone oxidoreductase subunit M -
HZF02_RS19090 4158963..4160426 + 1464 WP_155583983.1 NADH-quinone oxidoreductase subunit NuoN -
HZF02_RS19095 4160666..4161016 + 351 WP_179451113.1 toxin Toxin
HZF02_RS19100 4161006..4161320 + 315 WP_155583981.1 transcriptional regulator Antitoxin
HZF02_RS19105 4161434..4163176 - 1743 WP_179447221.1 ABC transporter substrate-binding protein -
HZF02_RS19110 4163222..4163494 - 273 WP_155583979.1 DUF2160 domain-containing protein -
HZF02_RS19115 4163505..4164305 - 801 WP_155583978.1 carbohydrate ABC transporter permease -
HZF02_RS19120 4164316..4165182 - 867 WP_010173085.1 sugar ABC transporter permease -
HZF02_RS19125 4165179..4166276 - 1098 WP_179447222.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13768.71 Da        Isoelectric Point: 9.9311

>T166987 WP_179451113.1 NZ_CP058644:4160666-4161016 [Pseudomonas yamanorum]
MDALFIELPPFERYRRDYLSDELFHGFQQALMRNPQAGDVIEGTGGLRKVRFVDERRNKGKRGGLRVIYYWWSGGTQFWL
FTLYGKHEQDDLTPPHKKALKQMLDREIKARTPHET

Download         Length: 351 bp

>T166987 NZ_CP074578:c5428672-5428382 [Pseudomonas syringae]
ATGACCTATAACCTCGAATTCGATGCGCGGGCTCTAAAGGAATGGCACAAATTAGGGGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCCAATCGTCTGCATGCATTGCCTGACTGCTACAAAATCA
AACTGCGCAGTAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGAGGAGGTTTACCGTAAGGCTGCTGATCGGTTGGGCGGGTAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11755.57 Da        Isoelectric Point: 10.3438

>AT166987 WP_155583981.1 NZ_CP058644:4161006-4161320 [Pseudomonas yamanorum]
MKRDIFSELVEGLEALADERQGKVTLRTHKVHLNKLAPLTAEEVVAVRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQAATLIRLVAKFPETVERLAALT

Download         Length: 315 bp

>AT166987 NZ_CP074578:c5428901-5428662 [Pseudomonas syringae]
ATGGCGTCTATCAACGTTCGTATCGACGACGATCTCAAAGCGCGTGCTTACCTTGAGCTGGAAAAGCTTGGCGTCACCCC
CTCGGAGTTGCTGCGCCAAACCCTGCAGTACGTAGCTGAGCGTGGCCAGCTGCCCTTCAAGACGGTTCTGATGACAGAGG
AAGACGAAGCGCTGTTGGCAACTGTGCGCGAGCGCCTTGCAGCTCCGCAGCGGGTCAAGGTTTCACTGGATGACCTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References