Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2099189..2099460 Replicon chromosome
Accession NZ_CP058342
Organism Escherichia coli strain W60

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2099319..2099422 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2099189..2099460 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HXP40_RS09895 2095744..2096406 - 663 WP_000944256.1 exodeoxyribonuclease X -
HXP40_RS09900 2096430..2097086 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
HXP40_RS09905 2097188..2097418 - 231 WP_000916763.1 DNA polymerase III subunit theta -
HXP40_RS09910 2097557..2097931 + 375 WP_000168747.1 CopC domain-containing protein YobA -
HXP40_RS09915 2097935..2098807 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
HXP40_RS09920 2098820..2099161 + 342 WP_000976476.1 YebY family protein -
- 2099189..2099460 - 272 - - Antitoxin
- 2099319..2099422 + 104 - - Toxin
HXP40_RS09925 2099557..2100213 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
HXP40_RS09930 2100214..2100405 - 192 WP_000457842.1 YebW family protein -
HXP40_RS09935 2100510..2100746 - 237 WP_001295499.1 DUF1480 family protein -
HXP40_RS09940 2100864..2102303 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T166603 NZ_CP058342:2099319-2099422 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT166603 NZ_CP058342:c2099460-2099189 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References