Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2033822..2033963 Replicon chromosome
Accession NZ_CP057864
Organism Citrobacter freundii strain RHB12-C19

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2033857..2033960 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2033822..2033963 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVW68_RS09600 2030269..2030931 - 663 WP_003841659.1 exodeoxyribonuclease X -
HVW68_RS09605 2030955..2031611 - 657 WP_046671220.1 carbon-nitrogen hydrolase family protein -
HVW68_RS09610 2031718..2031948 - 231 WP_106902137.1 DNA polymerase III subunit theta -
HVW68_RS09615 2032092..2032466 + 375 WP_181826147.1 CopC domain-containing protein YobA -
HVW68_RS09620 2032470..2033342 + 873 WP_003034931.1 copper homeostasis membrane protein CopD -
HVW68_RS09625 2033363..2033701 + 339 WP_181826148.1 YebY family protein -
- 2033822..2033963 - 142 - - Antitoxin
- 2033857..2033960 + 104 - - Toxin
HVW68_RS09630 2034093..2035172 - 1080 WP_016150458.1 phage integrase Arm DNA-binding domain-containing protein -
HVW68_RS09635 2035150..2035410 - 261 WP_072211989.1 hypothetical protein -
HVW68_RS09640 2035474..2037945 - 2472 WP_060855113.1 exonuclease -
HVW68_RS09645 2038087..2038413 - 327 WP_060855149.1 Rrf2 family transcriptional regulator -
HVW68_RS09650 2038475..2038687 - 213 WP_153070801.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2026618..2087771 61153


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T165726 NZ_CP057864:2033857-2033960 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 142 bp

>AT165726 NZ_CP057864:c2033963-2033822 [Citrobacter freundii]
GATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References