Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 791407..792061 Replicon chromosome
Accession NZ_CP057258
Organism Citrobacter freundii strain RHB31-C16

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag HVY90_RS03935 Protein ID WP_096755799.1
Coordinates 791654..792061 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag HVY90_RS03930 Protein ID WP_096755798.1
Coordinates 791407..791673 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HVY90_RS03905 786621..788054 - 1434 WP_115257538.1 6-phospho-beta-glucosidase BglA -
HVY90_RS03910 788175..788903 - 729 WP_115259901.1 MurR/RpiR family transcriptional regulator -
HVY90_RS03915 788956..789267 + 312 WP_096755795.1 N(4)-acetylcytidine aminohydrolase -
HVY90_RS03920 789431..790090 + 660 WP_096755796.1 hemolysin III family protein -
HVY90_RS03925 790170..791150 - 981 WP_115257540.1 tRNA-modifying protein YgfZ -
HVY90_RS03930 791407..791673 + 267 WP_096755798.1 FAD assembly factor SdhE Antitoxin
HVY90_RS03935 791654..792061 + 408 WP_096755799.1 protein YgfX Toxin
HVY90_RS03940 792107..792628 - 522 WP_096755800.1 flavodoxin FldB -
HVY90_RS03945 792741..793637 + 897 WP_096755801.1 site-specific tyrosine recombinase XerD -
HVY90_RS03950 793661..794374 + 714 WP_181688757.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
HVY90_RS03955 794380..796113 + 1734 WP_137399032.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15935.93 Da        Isoelectric Point: 11.2851

>T165133 WP_096755799.1 NZ_CP057258:791654-792061 [Citrobacter freundii]
VVQWQSDLRVSWRAQWISLLIHGLVAVLILLMPWPLSYTPLWLILLSLVVFDCVRSQRRINACQGEIRLLMDGRLRWQGQ
EWSIVSAPWMIKTGMMLRLRSSTGKRQHLWLAADSMDDAEWRDLRRLILQPSMQK

Download         Length: 408 bp

>T165133 NZ_CP073718:c828850-828473 [Escherichia coli]
ATGAAAACATTACCCGACACACACGTACGGGAGGCATCGCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTGTC
CCGGTTGCTGGACCAGCATTACGGCCTTACGCTGAATGACACACCGTTCGCCGATGAACGTGTGATTGAGCAGCATATTG
AAGCTGGCATTTCACTGTGTGATGCGGTGAACTTTCTCGTTGAAAAATACGCACTGGTACGTACCGACCAGCCGGGATTC
AGCGCCTGTACCCGCTCTCAGTTAATAAACAGTATTGATATTCTCCGGGCTCGCAGGGCAACCGGCCTGATGACCCGCGA
TAACTACAGAACGGTAAATAACATTACCCAGGGGAAGCATCCGGAGGCGAAACAATGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10570.10 Da        Isoelectric Point: 5.6311

>AT165133 WP_096755798.1 NZ_CP057258:791407-791673 [Citrobacter freundii]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDNLSDDEKRIFIRLLECDDPDLFNWLMNHGKPADAQLEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp

>AT165133 NZ_CP073718:c829266-828940 [Escherichia coli]
ATGAGCAACCCTACCAGGGGCCTGCAGCGGGAGATTACACTGCGCCTGGGAGCCCGTCTGGTGCAGGAAGGCAACCGACT
GCATTATCTGGCTGACCGGGCCAGCATCACCGGCAAGTTCAGTGACATCGAATGCCGGAAGCTGGATGAAACATTCCCGC
ACTTTATCCGCCAGATGGAATCGATGCTGACCACCGGTGAACTCAGCCCCCACCATGCCCACTGCGTTACCCTGTACCAC
AACGATTTAACCTGCGAAGCCGACACCTTCGGCTCCTGTGGTTACGTTTATCTGGCTGTTTATCCGACGCCCGAAACGAA
AAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References