Detailed information of TA system TA164151

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1638536..1639449
• Replicon: chromosome
• Accession: NZ_CP056756
• Organism: Enterobacter hormaechei strain RHBSTW-00198

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HV117_RS07910
• Protein ID: WP_047052345.1
• Coordinates: 1638536..1639009 (-)
• Length: 158 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: HV117_RS07915
• Protein ID: WP_047052347.1
• Coordinates: 1639006..1639449 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
HV117_RS07890	1634695..1636005	+	1311	WP_047052339.1	type I-F CRISPR-associated protein Csy1	-
HV117_RS07895	1636002..1636937	+	936	WP_047052340.1	type I-F CRISPR-associated protein Csy2	-
HV117_RS07900	1636951..1637949	+	999	WP_047052342.1	type I-F CRISPR-associated protein Csy3	-
HV117_RS07905	1637959..1638513	+	555	WP_047052344.1	type I-F CRISPR-associated endoribonuclease Cas6/Csy4	-
HV117_RS07910	1638536..1639009	-	474	WP_047052345.1	RES domain-containing protein	Toxin
HV117_RS07915	1639006..1639449	-	444	WP_047052347.1	DUF2384 domain-containing protein	Antitoxin
HV117_RS07920	1641401..1641619	-	219	WP_002211347.1	translation initiation factor IF-1	-
HV117_RS07925	1641904..1642608	-	705	WP_047052381.1	leucyl/phenylalanyl-tRNA--protein transferase	-
HV117_RS07930	1642654..1644375	-	1722	WP_003858307.1	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre/MbcA/ParS-like, toxin-binding domain (94-144)

Sequences

Toxin

Protein

• Length: 158 a.a.
• Molecular weight: 17570.95 Da
• Isoelectric Point: 5.1151

>T164151 WP_047052345.1 NZ_CP056756:c1639009-1638536 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFDFDTRLAEKTAP

Nucleotide

• Length: 474 bp

>T164151 NZ_CP072801:c3717195-3716944 [Thiothrix litoralis]
ATGAACGCCATCTCCTACACCGCTGTGCGAGCGGAACTCGCCAAAACGATGGATCGGGTCTGCGAAGATCACGAACCCAT
CATCATTACCCGCAACCGCGAACAAGCCGTCGTCATGATTTCGTTGGAAGATTACAAAGCGATGGAAGAAACCGCCTATT
TGTTGCGTAGCCCAGCTAATGCCAGTCGCTTGCTGGAATCCATTGCTGAATTGGGGCGTGGGAATGGGCAAGCGCGAGAG
TTGCTGGAATGA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16502.77 Da
• Isoelectric Point: 6.4819

>AT164151 WP_047052347.1 NZ_CP056756:c1639449-1639006 [Enterobacter hormaechei]
MRTWVPAQRSADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Nucleotide

• Length: 444 bp

>AT164151 NZ_CP072801:c3716947-3716693 [Thiothrix litoralis]
ATGAGGATAGTTTTTTCATCCAAAGCGTGGGAAGACTATCTGTACTGGCAGCAAGCCGACAAGAAAATCCTGAAACGCAT
CAATGAGTTGATCAAGGCGATTTCCCGCGAGCCATTTGAGGGTATCGGTAAGCCCGAACCGTTGCGGCATGGCTTGTCCG
GCTATTGGTCACGACGGATCAATGATGAACATCGCTTGGTCTACAAGGTGGAAGGTGAGGATTTACTGATCGCTATGTGC
CGCTACCATTATTAA