Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 3103871..3104784 Replicon chromosome
Accession NZ_CP056742
Organism Enterobacter hormaechei strain RHBSTW-00220

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag HV132_RS15085 Protein ID WP_047052345.1
Coordinates 3104311..3104784 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag HV132_RS15080 Protein ID WP_047052347.1
Coordinates 3103871..3104314 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV132_RS15065 3098945..3100666 + 1722 WP_003858307.1 cysteine/glutathione ABC transporter ATP-binding protein/permease CydC -
HV132_RS15070 3100712..3101416 + 705 WP_047052381.1 leucyl/phenylalanyl-tRNA--protein transferase -
HV132_RS15075 3101701..3101919 + 219 WP_002211347.1 translation initiation factor IF-1 -
HV132_RS15080 3103871..3104314 + 444 WP_047052347.1 DUF2384 domain-containing protein Antitoxin
HV132_RS15085 3104311..3104784 + 474 WP_047052345.1 RES domain-containing protein Toxin
HV132_RS15090 3104807..3105361 - 555 WP_047052344.1 type I-F CRISPR-associated endoribonuclease Cas6/Csy4 -
HV132_RS15095 3105371..3106369 - 999 WP_047052342.1 type I-F CRISPR-associated protein Csy3 -
HV132_RS15100 3106383..3107318 - 936 WP_047052340.1 type I-F CRISPR-associated protein Csy2 -
HV132_RS15105 3107315..3108625 - 1311 WP_181522297.1 type I-F CRISPR-associated protein Csy1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(94-144)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 17570.95 Da        Isoelectric Point: 5.1151

>T164094 WP_047052345.1 NZ_CP056742:3104311-3104784 [Enterobacter hormaechei]
MIFYRLVTGRFASEAWSGSGANQYGGRWNHKGHPAVYVSTSISLASLEILVHVRKDTVLNQYQLFSINIPDDQIDYLDKA
WLPEDWQENPAPVSTMDLGTGWLQANSALALILPSCIIPYENNAILNPLHPAFRKALNSVELLPFDFDTRLAEKTAP

Download         Length: 474 bp

>T164094 NZ_CP072790:2803707-2804132 [Mycobacterium tuberculosis]
GTGGCGCTGCTCGACGTCAACGCATTGGTCGCGCTGGCGTGGGACTCACACATCCACCACGCCCGGATCCGCGAGTGGTT
TACCGCCAACGCCACGCTCGGCTGGGCGACTTGCCCGCTCACCGAAGCCGGCTTCGTGCGGGTGTCGACGAACCCAAAAG
TACTTCCCAGCGCGATCGGGATCGCAGACGCTCGACGGGTCCTCGTGGCACTACGCGCCGTGGGAGGCCACCGCTTCCTG
GCTGACGACGTATCGCTCGTCGATGACGATGTTCCGTTGATCGTCGGTTATCGCCAGGTGACCGACGCCCATCTGCTGAC
ACTCGCCCGCCGGCGCGGCGTCCGCCTGGTCACCTTCGACGCCGGTGTCTTCACCCTCGCCCAACAACGCCCCAAGACGC
CAGTGGAGCTGCTGACCATCCTCTAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16502.77 Da        Isoelectric Point: 6.4819

>AT164094 WP_047052347.1 NZ_CP056742:3103871-3104314 [Enterobacter hormaechei]
MRTWVPAQRSADNTLWRYAGLPASRGMRLIEYLNQGLPVSVLDNIHEWTDMSKAEILRVTGINERNVARRKSTGRTLTPD
ESERVARFVRVLDAAVDYFGSKEEAWNWLQLPVRGLGNVAPVDLIATETGALEVTDLIGRLEHGVFA

Download         Length: 444 bp

>AT164094 NZ_CP072790:2803480-2803701 [Mycobacterium tuberculosis]
GTGCGAACGACACTTGACCTTGACGACGATGTGATCGCCGCGGCACGTGAACTTGCCTCCAGCCAGCGCCGCTCGCTCGG
CTCGGTGATTTCCGAACTCGCACGCCGTGGTCTCATGCCCGGACGCGTCGAGGCTGACGACGGGCTGCCGGTGATCCGCG
TTCCAGCCGGGACCCCGCCGATCACACCGGAGATGGTCCGTCGCGCGCTCGATGAGGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References