Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2152683..2152851 Replicon chromosome
Accession NZ_CP056701
Organism Klebsiella grimontii strain RHBSTW-00577

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2152741..2152844 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2152683..2152851 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV240_RS10360 2147810..2149870 + 2061 WP_049085565.1 oligopeptidase B -
HV240_RS10365 2149877..2150536 - 660 WP_004134816.1 exodeoxyribonuclease X -
HV240_RS10370 2150615..2150845 - 231 WP_004103351.1 DNA polymerase III subunit theta -
HV240_RS10375 2150981..2151355 + 375 WP_049085566.1 CopC domain-containing protein YobA -
HV240_RS10380 2151360..2152229 + 870 WP_004134819.1 copper homeostasis membrane protein CopD -
HV240_RS10385 2152246..2152584 + 339 WP_004103344.1 YebY family protein -
- 2152683..2152851 - 169 - - Antitoxin
- 2152741..2152844 + 104 - - Toxin
HV240_RS10390 2152969..2153928 - 960 WP_049085573.1 spore coat U domain-containing protein -
HV240_RS10395 2153943..2156273 - 2331 WP_082237025.1 fimbrial biogenesis outer membrane usher protein -
HV240_RS10400 2156276..2157040 - 765 WP_004134823.1 molecular chaperone -
HV240_RS10405 2157059..2157577 - 519 WP_032711055.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2147756..2166310 18554


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T163939 NZ_CP056701:2152741-2152844 [Klebsiella grimontii]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT163939 NZ_CP056701:c2152851-2152683 [Klebsiella grimontii]
AATAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGTGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References