Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1892727..1892872 Replicon chromosome
Accession NZ_CP056191
Organism Klebsiella pneumoniae strain RHBSTW-00995

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1892763..1892865 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1892727..1892872 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV347_RS09245 1887857..1889917 + 2061 WP_004151449.1 oligopeptidase B -
HV347_RS09250 1889921..1890580 - 660 WP_002911407.1 exodeoxyribonuclease X -
HV347_RS09255 1890659..1890889 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HV347_RS09260 1891002..1891376 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HV347_RS09265 1891380..1892249 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
HV347_RS09270 1892266..1892604 + 339 WP_016529031.1 YebY family protein -
- 1892727..1892872 - 146 - - Antitoxin
- 1892763..1892865 + 103 - - Toxin
HV347_RS09275 1893239..1893382 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HV347_RS09280 1893487..1894455 - 969 WP_004151446.1 VirK/YbjX family protein -
HV347_RS09285 1894612..1895265 + 654 WP_032447686.1 protein-serine/threonine phosphatase -
HV347_RS09290 1895262..1895453 - 192 WP_002911395.1 YebW family protein -
HV347_RS09295 1895551..1895790 - 240 WP_002911393.1 YebV family protein -
HV347_RS09300 1895906..1897339 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T162934 NZ_CP056191:1892763-1892865 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT162934 NZ_CP056191:c1892872-1892727 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References