Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 3479031..3479715 Replicon chromosome
Accession NZ_CP056132
Organism Enterobacter hormaechei strain RHBSTW-00916

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag HV326_RS16700 Protein ID WP_181522519.1
Coordinates 3479392..3479715 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag HV326_RS16695 Protein ID WP_101862777.1
Coordinates 3479031..3479354 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HV326_RS16665 3474515..3474955 + 441 WP_101863233.1 hypothetical protein -
HV326_RS16670 3474991..3475353 + 363 WP_101863232.1 hypothetical protein -
HV326_RS16675 3475682..3476878 - 1197 WP_181522411.1 HNH endonuclease -
HV326_RS16680 3477458..3478276 + 819 WP_101862774.1 DUF945 domain-containing protein -
HV326_RS16685 3478309..3478779 + 471 WP_101862775.1 DNA repair protein RadC -
HV326_RS16690 3478788..3479009 + 222 WP_101862776.1 DUF987 family protein -
HV326_RS16695 3479031..3479354 + 324 WP_101862777.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
HV326_RS16700 3479392..3479715 + 324 WP_181522519.1 TA system toxin CbtA family protein Toxin
HV326_RS16705 3480229..3481467 + 1239 WP_047729546.1 ribokinase -
HV326_RS16710 3481535..3482512 + 978 WP_080350787.1 sugar ABC transporter permease -
HV326_RS16715 3482512..3483411 + 900 WP_045339512.1 carbohydrate ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(10-106)

Antitoxin

Antitoxin CbeA

(4-102)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12137.81 Da        Isoelectric Point: 5.5881

>T162735 WP_181522519.1 NZ_CP056132:3479392-3479715 [Enterobacter hormaechei]
ISSVPATVPVSSRLSPVQVWQQLLTYLLEQHYGLTLNDTPFHDDTAIEEHIDAGITLADAVNFLVEKYELVRIDRKGFSW
QEQTPYISVVDILRARRSTGLLKTNVK

Download         Length: 324 bp

>T162735 NZ_CP071988:991510-991689 [Staphylococcus epidermidis]
ATGGCGAACAAAAAAGATTCCAAATTAAATTATCATGAAGAAGAAAATGCTATGGTTACCGACTTAGATGATTTAAAAGA
ATTAGGAAAAGAAATGGAACAGATTTCACAGGAAAATGATGAAGAAAAATTAAATCAATCTCATGATAACGAAGTTCGTT
CAGATTTAAAAAAACAGTAA

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11983.69 Da        Isoelectric Point: 7.0268

>AT162735 WP_101862777.1 NZ_CP056132:3479031-3479354 [Enterobacter hormaechei]
MQNSWGLKRDISPCFGARLVQEGCRLHFLADRAGISGTFNKDETLRLDQAFPLVMKQLELMLTTGELNPRHQHCVTLHHN
GLTCEADTLGSHGYVYIVIYPQASATQ

Download         Length: 324 bp

>AT162735 NZ_CP071988:990887-991486 [Staphylococcus epidermidis]
ATGGCAATGAATTTTAAAGTATTTGATAATAGTGAAAAAGTAGCAGAATATACTGCAGATATTCTACGTAAGCAATTTAA
TAATAATCCAACTACTATTGCAGGATTTCATTTGAGCAAAGAACATGCACCAGTGTTTGATGAACTTAAGAAAAATGTAG
AAAATCATACAGTTGATTTCAGTCAAATAAATATTTTAGATTATGATGATAATCATTCTTATTATGAGGCTTTGGGTGTG
CCAACAGGCCAAATTTATTCCATTTCTTACGAAAATGATGCAATTGACTTTATCTCAGATAAGATTAAGACTAAAGAAAA
TAAAGGCAAACTGACAATGCAAGTCCTTACGATTGATGAAAATGGTAAACTTGACATTAGCGTTCGTCAAGGTTTGATGG
AAGCTAGAGAAATTTTCTTAGTTATTACTGGTGCTAATAAACGCGATATGGTAGAAAAACTTTACCGTGAAAATGGTAAG
ACTAGTTTTGAACCATCGGATTTAAAAGCACACCGTATGGTCAATGTTATCTTAGATAAAGAAGCGGCTGCAGGCTTACC
TGAAGACGTAAAAGAGTACTTCACTGCACGTTTTGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References