Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1914818..1914963 Replicon chromosome
Accession NZ_CP055003
Organism Klebsiella pneumoniae strain STIN_79

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1914854..1914956 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1914818..1914963 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUZ54_RS09365 (HUZ54_09360) 1909948..1912008 + 2061 WP_004151449.1 oligopeptidase B -
HUZ54_RS09370 (HUZ54_09365) 1912012..1912671 - 660 WP_021440386.1 exodeoxyribonuclease X -
HUZ54_RS09375 (HUZ54_09370) 1912750..1912980 - 231 WP_002911406.1 DNA polymerase III subunit theta -
HUZ54_RS09380 (HUZ54_09375) 1913093..1913467 + 375 WP_004151448.1 CopC domain-containing protein YobA -
HUZ54_RS09385 (HUZ54_09380) 1913471..1914340 + 870 WP_021440385.1 copper homeostasis membrane protein CopD -
HUZ54_RS09390 (HUZ54_09385) 1914357..1914695 + 339 WP_239619694.1 YebY family protein -
- 1914818..1914963 - 146 - - Antitoxin
- 1914854..1914956 + 103 - - Toxin
HUZ54_RS09395 (HUZ54_09390) 1915332..1915475 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
HUZ54_RS09400 (HUZ54_09395) 1915580..1916548 - 969 WP_014907334.1 VirK/YbjX family protein -
HUZ54_RS09405 (HUZ54_09400) 1916705..1917358 + 654 WP_021440384.1 protein-serine/threonine phosphatase -
HUZ54_RS09410 (HUZ54_09405) 1917355..1917546 - 192 WP_002911395.1 YebW family protein -
HUZ54_RS09415 (HUZ54_09410) 1917644..1917883 - 240 WP_002911393.1 YebV family protein -
HUZ54_RS09420 (HUZ54_09415) 1917999..1919432 - 1434 WP_021440382.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T160918 NZ_CP055003:1914854-1914956 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT160918 NZ_CP055003:c1914963-1914818 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References