Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4496751..4497405 Replicon chromosome
Accession NZ_CP054871
Organism Pseudomonas protegens strain PPRAR07

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag HUT23_RS20315 Protein ID WP_053152689.1
Coordinates 4496751..4497101 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag HUT23_RS20320 Protein ID WP_210458376.1
Coordinates 4497088..4497405 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUT23_RS20305 (HUT23_20305) 4493510..4495042 + 1533 WP_015636298.1 NADH-quinone oxidoreductase subunit M -
HUT23_RS20310 (HUT23_20310) 4495050..4496513 + 1464 WP_015636299.1 NADH-quinone oxidoreductase subunit NuoN -
HUT23_RS20315 (HUT23_20315) 4496751..4497101 + 351 WP_053152689.1 hypothetical protein Toxin
HUT23_RS20320 (HUT23_20320) 4497088..4497405 + 318 WP_210458376.1 transcriptional regulator Antitoxin
HUT23_RS20325 (HUT23_20325) 4497478..4498860 - 1383 WP_123430474.1 cysteine--tRNA ligase -
HUT23_RS20330 (HUT23_20330) 4498879..4500579 - 1701 WP_174395733.1 glutamine--tRNA ligase/YqeY domain fusion protein -
HUT23_RS20335 (HUT23_20335) 4500850..4501353 + 504 WP_011062201.1 peptidylprolyl isomerase -
HUT23_RS20340 (HUT23_20340) 4501350..4502102 + 753 WP_174395732.1 UDP-2,3-diacylglucosamine diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(48-101)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13936.07 Da        Isoelectric Point: 9.6226

>T160557 WP_053152689.1 NZ_CP054871:4496751-4497101 [Pseudomonas protegens]
MNALFIELPAFARYRKGFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFIDERRNKGRRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT

Download         Length: 351 bp

>T160557 NZ_CP070569:1916545-1917069 [Proteus mirabilis]
ATGACAATACCAAATTGGCACGAAGAAGCGATCAGTAAAAAACATAATAGAAATGGATTTAATTGTGGCGATGCAGTACT
AAACCAATTTCTGTATCGCCATGCAAGACAAAATCATGAGAATGGTAGTGCGAAAACATATTTAGCTATCAATAATAGTA
ATAATATTATATTAGGTTATTACAGCTTATGTCCTGCTTCTATTGAGTTCGAAAGAACGCCCGAATTGATCAAACATGGC
TTAGCGCGTCATGATATCCCTGTTTTTAAACTTGCACGACTAGCTACGGATCTATCCGTTCAAGGAAAAGGTTTGGGTGG
GCAATTATTGCTTGCAGCAGGAAGGCGTTGTCTTTCCGTTGCTAGTGAATTGGGAGGCGTTGCTTTACTTATAGATGCTA
AAAATGAACGAGTCGCTAATTGGTATATTAGCTACGGGGCAATACCATTATTAGATACCCCTCTTTCTTTATTAATTTCC
TTTAAAACCATTTATACTGCACTTTCAATGGCAAATAAAATATAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12068.96 Da        Isoelectric Point: 10.4439

>AT160557 WP_210458376.1 NZ_CP054871:4497088-4497405 [Pseudomonas protegens]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITAAEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRAIP
NAQATTLMRLVERYPDTVERLASLA

Download         Length: 318 bp

>AT160557 NZ_CP070569:1916270-1916548 [Proteus mirabilis]
ATGGCTCAAGCACTAGTAGAAAACAGTGAACGAGTGTCAATTCGTATCACTACAGAAGATAAATCACTGCTGGTTCGTGC
TGCTAGTTTGGAAAATACAAACTTAACAGAGTTTGTACTTCGTAATATTGTACCTGTAGCTCGGCAAGTTATTGAAAATA
ATGAGCGTTTAAAATTATCAGAAAAAGACACATTACGTGTTATGGAACTTTTAGATAATCCACCAAAGCCTAATGCTAAA
CTACTTGCAGCGGCTTTTGCTCTACCGGACAATGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References