Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907-MazE
Location 1145074..1145648 Replicon chromosome
Accession NZ_CP054619
Organism Azospirillum oryzae strain KACC 14407

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag HUE56_RS14530 Protein ID WP_149198276.1
Coordinates 1145074..1145409 (-) Length 112 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag HUE56_RS14535 Protein ID WP_149198277.1
Coordinates 1145409..1145648 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HUE56_RS14505 1140207..1141550 + 1344 WP_149198271.1 oxalate/formate MFS antiporter -
HUE56_RS14510 1141633..1141854 - 222 WP_149198272.1 hypothetical protein -
HUE56_RS14515 1142167..1143852 + 1686 WP_149198273.1 alpha-amylase family protein -
HUE56_RS14520 1143881..1144318 - 438 WP_149198274.1 helix-turn-helix transcriptional regulator -
HUE56_RS14525 1144452..1145063 + 612 WP_149198275.1 NAD(P)-dependent oxidoreductase -
HUE56_RS14530 1145074..1145409 - 336 WP_149198276.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
HUE56_RS14535 1145409..1145648 - 240 WP_149198277.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
HUE56_RS14540 1145736..1147649 - 1914 WP_149198278.1 DNA mismatch repair endonuclease MutL -
HUE56_RS14545 1147710..1148075 - 366 WP_149198279.1 hypothetical protein -
HUE56_RS14550 1148323..1149558 + 1236 WP_149198280.1 DUF3095 family protein -
HUE56_RS14555 1149586..1150293 - 708 WP_174757242.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-109)

Antitoxin

Antitoxin PemI-like

(1-78)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 12019.09 Da        Isoelectric Point: 9.8035

>T159981 WP_149198276.1 NZ_CP054619:c1145409-1145074 [Azospirillum oryzae]
MLPDRGDLVWIDFTPQAGHEQAGRHPGLVLSPRAYHNRTPFVVVCPITSKVKGYPFEVALPPGLPVGGVVLADQVKSLDR
RVRQLDPAGSVPEAVLQQVLAKLAPLLSLRL

Download         Length: 336 bp

>T159981 NZ_CP070229:3317525-3317902 [Escherichia coli]
ATGACCATTCAGTTTATCTCTGCGGAGGAGATAATTTATTTCCACGATAAGTTGCTTAGCGTTACACCAGGTGTAACAGG
AATGTCCGATCCAGGGCGAGCAGAAGCGCTTTTGTACCGGGTACTGAATAAGTACGAGTATGAAGGCGTTTCCGATCTTT
GGCTGCTGGCGGCGATGCATCTATTGGCAATCTCGCGCGGTCATATTTTTAATGATGGTAATAAGCGCACCGCACTGTTT
ATCACGCTATTATTCCTTAAACGTAACGGCCTCATACTTGCTGCAAACCCAGAGTTTGTGGAATTGACGGTTGATGTGGC
GGCGGGAAAAGTATCGTTAGAAGATATCGTTACCCGCTTGCGTCAACACGGAACCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8731.75 Da        Isoelectric Point: 4.0297

>AT159981 WP_149198277.1 NZ_CP054619:c1145648-1145409 [Azospirillum oryzae]
MRTEVARWGNSLALRLPRPIADQTGFAEGTPVEIEVEDGRIVIRPATPRYALDDLLAGITADNLPDESFDDEPRGQELL

Download         Length: 240 bp

>AT159981 NZ_CP070229:3317307-3317528 [Escherichia coli]
ATGCATACCATGAACTACAGCGAAGCGCGACAGAACCTTGCATTGGTTCTGGAAACAGCGGCGACAGGTACTCCGGTAAC
GATCACGAGGCGTGGGCATAAGGCCGCTGTGATTATTAGCGCAGAAGAGTTTGAACGTTACCAGAAGGCTAAACTGGACG
CGGAATTTGACGCCATCATGGCTATTCATGGCAGCGAAATTATGGAGTTAGCGGATAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References