Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1007587..1008110 Replicon chromosome
Accession NZ_CP054150
Organism Agrobacterium vaccinii strain B7.6

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HRR99_RS05115 Protein ID WP_233123013.1
Coordinates 1007587..1007874 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag HRR99_RS05120 Protein ID WP_233123014.1
Coordinates 1007871..1008110 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HRR99_RS05095 (HRR99_05080) 1003295..1004140 - 846 WP_233123009.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
HRR99_RS05100 (HRR99_05085) 1004158..1006356 + 2199 WP_233123010.1 molybdopterin oxidoreductase family protein -
HRR99_RS05105 (HRR99_05090) 1006368..1006964 + 597 WP_233123011.1 NUDIX domain-containing protein -
HRR99_RS05110 (HRR99_05095) 1006979..1007590 + 612 WP_233123012.1 NUDIX domain-containing protein -
HRR99_RS05115 (HRR99_05100) 1007587..1007874 - 288 WP_233123013.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HRR99_RS05120 (HRR99_05105) 1007871..1008110 - 240 WP_233123014.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
HRR99_RS05125 (HRR99_05110) 1008176..1008835 - 660 WP_233123015.1 phosphoribosylglycinamide formyltransferase -
HRR99_RS05130 (HRR99_05115) 1008832..1009905 - 1074 WP_233123016.1 phosphoribosylformylglycinamidine cyclo-ligase -
HRR99_RS05135 (HRR99_05120) 1010143..1011297 + 1155 WP_111839682.1 AI-2E family transporter -
HRR99_RS05140 (HRR99_05125) 1011302..1012015 + 714 WP_233123017.1 DnaA regulatory inactivator HdaA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(1-75)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10726.32 Da        Isoelectric Point: 8.5519

>T158790 WP_233123013.1 NZ_CP054150:c1007874-1007587 [Agrobacterium vaccinii]
MKALLLTPKARSDIEGIWDYTVDNWGINQAEVYITAIQKALEGLADGSTISQSAESIRKHYRKTIVGSHTVFFKETDAAI
EVVRILHHRMSLTRL

Download         Length: 288 bp

>T158790 NZ_CP069821:c4571687-4571277 [Klebsiella pneumoniae]
GTGGTCCTGTGGCAATCTGATCTCCGTATCTCCTGGCGCGCGCAGTGGTTTTCCCTGCTGCTTCACGGCGTGGTGGCGGC
CCTGGTGCTGTTGGTTCCCTGGCCGCTGAGCTATACCCCGATCTGGCTGCTGCTGCTGTCGCTGGTGGTCTTCGACTGCG
TGCGCAGCCAGCGGCGGATCCATGCCCGTCGCGGGGAGATAAAACTGCTCACCGATTCCCGTCTTCGCTGGCAAAACGCC
GAATGGGAGATCCTCGGGACGCCGTGGGTTATCAATAGCGGTATGCTGCTGCGTTTGCGCCATGTCGATACCCGGCGCGG
ACAGCATCTTTGGCTGGCGGCGGACAGCATGGACGCCGGAGAGTGGCGCGATCTGCGCCGGCTGGTGCTGCAAAAACCGG
CGCAGGAGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8834.88 Da        Isoelectric Point: 5.1585

>AT158790 WP_233123014.1 NZ_CP054150:c1008110-1007871 [Agrobacterium vaccinii]
MGKSTSVNLNDHFDAFIEQQIEDGRYASASEVLRAGLRLLEEREAELSHLRAALIEGEKSGDAVPFDFREFVRGKKKPG

Download         Length: 240 bp

>AT158790 NZ_CP069821:c4571934-4571668 [Klebsiella pneumoniae]
ATGGACATTAACAATAAAGCACGTATCCACTGGGCATGCCGCCGCGGGATGCGCGAACTCGACATCTCCATCATGCCGTT
CTTTGAGTATGAGTACGATACCCTCAGCGACGCTGACAAACAGCTGTTCATTCGCCTGCTGGAAAATGACGATCCGGATC
TGTTCAACTGGCTGATGAACCACGGCAAACCGGCCGATGCGGAGCTGCAGCGGATGGTAACCTTAATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References