Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 560481..561253 Replicon plasmid pPR13E02
Accession NZ_CP054033
Organism Rhizobium indicum strain JKLM 13E

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag FE844_RS32250 Protein ID WP_138331214.1
Coordinates 560765..561253 (+) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag FE844_RS32245 Protein ID WP_138331213.1
Coordinates 560481..560765 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FE844_RS32220 555661..556257 - 597 WP_138331210.1 SOS response-associated peptidase -
FE844_RS32225 556286..557116 - 831 WP_138331211.1 Ku protein -
FE844_RS32230 557126..558019 - 894 WP_173863102.1 Ku protein -
FE844_RS32235 558775..559089 + 315 WP_033183755.1 EamA family transporter -
FE844_RS32240 559238..559987 + 750 WP_138331212.1 sulfite exporter TauE/SafE family protein -
FE844_RS32245 560481..560765 + 285 WP_138331213.1 DUF1778 domain-containing protein Antitoxin
FE844_RS32250 560765..561253 + 489 WP_138331214.1 GNAT family N-acetyltransferase Toxin
FE844_RS32255 561511..561849 - 339 WP_138331215.1 helix-turn-helix domain-containing protein -
FE844_RS32260 562260..562472 - 213 WP_173863097.1 hypothetical protein -
FE844_RS32265 563104..563367 + 264 WP_064655279.1 DUF982 domain-containing protein -
FE844_RS32270 563448..563677 - 230 Protein_529 thermonuclease family protein -
FE844_RS32275 563674..563898 - 225 WP_138331217.1 hypothetical protein -
FE844_RS32280 563895..564209 - 315 WP_138331639.1 hypothetical protein -
FE844_RS32285 564290..564490 - 201 WP_138331218.1 hypothetical protein -
FE844_RS32290 564624..565672 + 1049 Protein_533 non-homologous end-joining DNA ligase -
FE844_RS32295 565718..566218 - 501 WP_138331640.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid - - 1..575483 575483


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(41-142)

Antitoxin

Vibrio phage ICP1, Orf50

(15-86)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17240.80 Da        Isoelectric Point: 7.4341

>T158540 WP_138331214.1 NZ_CP054033:560765-561253 [Rhizobium indicum]
MLSAPTLLGEAHDLQLFDSGHDSLDEWLRRRARANQVSGASRTYVVCEGERVVGYYCLSSGALAVADAPGAIRHNMPDPV
PMAVLGRLAIDRNWQGKGIGAALLQDAVLRTGQAAHIMGIRGLLVHAISDEAKAFYEHFGFAASPANPIALVLSLKAQVG
LK

Download         Length: 489 bp

>T158540 NZ_CP069666:2574929-2575036 [Escherichia coli O89m:H9]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10655.01 Da        Isoelectric Point: 8.6260

>AT158540 WP_138331213.1 NZ_CP054033:560481-560765 [Rhizobium indicum]
MTSKNATDTHTRAVNLRVRDDVRVLIDRAAKAHGKTRSDFMIDASRRAAEDALLDQTLVRVDPDSYKHYLAVLDQPPSSE
GFERLMNAPKPWHP

Download         Length: 285 bp

>AT158540 NZ_CP069666:c2574882-2574816 [Escherichia coli O89m:H9]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References