Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1870301..1870572 Replicon chromosome
Accession NZ_CP053600
Organism Escherichia coli strain Nico21(DE3)

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1870339..1870442 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1870301..1870572 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HO398_RS09285 1867458..1868897 + 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
HO398_RS09290 1869015..1869251 + 237 WP_001295499.1 DUF1480 family protein -
HO398_RS09295 1869356..1869547 + 192 WP_001296140.1 YebW family protein -
HO398_RS09300 1869548..1870204 - 657 WP_000812724.1 protein-serine/threonine phosphatase -
- 1870301..1870572 + 272 - - Antitoxin
- 1870339..1870442 - 104 - - Toxin
HO398_RS09305 1870599..1870940 - 342 WP_000976472.1 YebY family protein -
HO398_RS09310 1870953..1871825 - 873 WP_000879293.1 copper homeostasis membrane protein CopD -
HO398_RS09315 1871829..1872203 - 375 WP_000168747.1 CopC domain-containing protein YobA -
HO398_RS09320 1872342..1872572 + 231 WP_000916763.1 DNA polymerase III subunit theta -
HO398_RS09325 1872674..1873330 + 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
HO398_RS09330 1873354..1874016 + 663 WP_000944245.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T156983 NZ_CP053600:c1870442-1870339 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT156983 NZ_CP053600:1870301-1870572 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References